Inhibitory Effects of 1,3-Selenazol-4-one Derivatives on Mushroom Tyrosinase
スポンサーリンク
概要
- 論文の詳細を見る
This study reports depigmenting potency of 1,3-selenazol-4-one derivatives, which would be based upon the finding of direct inhibition to mushroom tyrosinase. 1,3-Selenazol-4-one derivatives exhibited inhibitory effect on dopa oxidase activity of mushroom tyrosinase. In this study, inhibitory effects of six kinds of 1,3-selenazol-4-one derivatives (A, B, C, D, E and F) on mushroom tyrosinase were investigated. Compounds at a concentration of 500 μM exhibited 33.4-62.1% of inhibition on dopa oxidase activity of mushroom tyrosinase. Their inhibitory effects were higher than that of kojic acid (31.7%), a well known tyrosinase inhibitor. 2-(4-Methylphenyl)-1,3-selenazol-4-one (A) exhibited the strongest inhibitory effect among them dose-dependently and in competitive inhibition manner.
- 社団法人日本薬学会の論文
- 2002-12-01
著者
-
KIM Sun
Graduate School of East-West Medicine, Kyung Hee University
-
Koike Minako
岐阜県国際バイオ研究所
-
Kim Sun
Graduate School Of East-west Medicine Kyung Hee Univ.
-
Choi Sang
韓国
-
Kim Sung-soo
Department Of Oriental Rehabilitation Medicine College Of Oriental Medicine Kyung Hee University
-
Kim Sung-soo
Department Of Applied Chemistry Graduate School Of Science And Engineering Tokyo Institute Of Techno
-
Kim H
Department Of Oriental Sports Medicine College Of Health & Therapy Daegu Haany University
-
Kim S
Graduate School Of East-west Medicine Kyung Hee Univ.
-
ISHIHARA Hideharu
Department of Chemistry, Faculty of Engineering, Gifu University
-
KOKETSU Mamoru
Department of Chemistry, Faculty of Engineering, Gifu University
-
CHOI Sang
Graduate School of East-West Medical Science, Kyung Hee University
-
LIM Beong
Graduate School of East-West Medical Science, Kyung Hee University
-
KIM Hocheol
Graduate School of East-West Medical Science, Kyung Hee University
-
Kim Sun
Graduate School Of East-west Medical Science Kyung Hee University
-
Lim Beong
Graduate School Of East-west Medical Science Kyung Hee University
-
Kim Hong
Department Of Oriental Sports Medicine College Of Health & Therapy Daegu Haany University
-
Kim S
Graduate School Of East-west Medical Science Kyung Hee University
-
Koketsu Mamoru
Department Of Chemistry Faculty Of Engineering Gifu University
-
Choi S
Kyung Hee Univ. Seoul Kor
-
Ishihara H
Drug Delivery Systme Institute Ltd. Building Of Research Institute For Biosciences The Science Unive
-
Kim H
Graduate School Of East-west Medical Science Kyung Hee University
-
Koketsu Mamoru
Research Center Suntory Limited
-
Kim Sun
Graduate School Of East-west Medical Science East-west Integrated Medical Science Research Center Ky
-
Kim Sun
East-west Integrated Medical Sci. Res. Center Kyung Hee Univ.
-
Ishihara Hideharu
Department Of Chemistry Faculty Of Engineering Gifu University
-
Ishihara Hideharu
Dep. Of Chemistry Fac. Of Engineering Gifu Univ.
-
Mamoru Koketsu
Research Center Suntory Limited
-
Kim Sun
Graduate School Of East-west Medical Science
関連論文
- Long-Term Clinical Course of Patients With Isolated Myocardial Bridge
- Protective Effects of Cinnamomum cassia Blume in the Fibrogenesis of Activated HSC-T6 Cells and Dimethylnitrosamine-Induced Acute Liver Injury in SD Rats
- Maternal ethanol administration inhibits 5-hydroxytryptamine synthesis and tryptophan hydroxylase expression in the dorsal raphe of rat offspring
- Maternal Alcohol Administration Suppresses Expression of Nitric Oxide Synthase in the Hippocampus of Offspring Rats
- Folium mori Increases Cell Proliferation and Neuropeptide Y Expression in Dentate Gyrus of Streptozotocin-Induced Diabetic Rats
- Effects of Paeonia radix on 5-Hydroxytryptamine Synthesis and Tryptophan Hydroxylase Expression in the Dorsal Raphe of Exercised Rats
- A dministration of Folium mori Extract Decreases Nitric Oxide Synthase Expression in the Hypothalamus of Streptozotocin-Induced Diabetic Rats
- Regulation of Melanin Synthesis by Selenium-Containing Carbohydrates
- Potent Inhibitory Effects of N-Aryl S-Alkylthiocarbamate Derivatives on the Dopa Oxidase Activity of Mushroom Tyrosinase
- The Effects of PVA/Chitosan/Fibroin (PCF)-Blended Spongy Sheets on Wound Heailng in Rats
- Inhibitory Effects of Whisky Congeners on Melanogenesis in Mouse B16 Melanoma Cells
- Ginseng radix Increases Cell Proliferation in Dentate Gyrus of Rats with Streptozotocin-Induced Diabetes
- Protective Effect of (4-Methoxybenzylidene)-(3-methoxynophenyl)amine against Neuronal Cell Death Induced by Oxygen and Glucose Deprivation in Rat Organotypic Hippocampal Slice Culture(Medicinal Chemistry)
- Inhibition of Tyrosinase Activity by N, N-Unsubstituted Selenourea Derivatives(Medicinal Chemistry)
- 1,3-Selenazol-4-one Derivatives Inhibit Inducible Nitric Oxide-Mediated Nitric Oxide Production in Lipopolysaccharide-Induced BV-2 Cells (Pharmacology)
- Inhibitory Effects of 1,3-Selenazol-4-one Derivatives on Mushroom Tyrosinase
- High-Dosage Pyridoxine-Induced Auditory Neuropathy and Protection with Coffee in Mice(Pharmacology)
- Protective Effect of Gabapentin on N-Methyl-D-aspartate-Induced Excitotoxicity in Rat Hippocampal CA1 Neurons
- Effect of postnatal treadmill exercise on c-Fos expression in the hippocampus of rat pups born from the alcohol-intoxicated mothers
- Maternal swimming during pregnancy enhances short-term memory and neurogenesis in the hippocampus of rat pups
- Influence of prenatal noise and music on the spatial memory and neurogenesis in the hippocampus of developing rats
- The Seed Extract of Cassia obtusifolia Ameliorates Learning and Memory Impairments Induced by Scopolamine or Transient Cerebral Hypoperfusion in Mice
- Effects of Anemarrhena asphodeloides on Focal Ischemic Brain Injury Induced by Middle Cerebral Artery Occlusion in Rats(Pharmacology)
- Enhancement of Neuroprotection of Mulberry Leaves (Morus alba L.) Prepared by the Anaerobic Treatment against Ischemic Damage(Pharmacology)
- Anxiolytic-Like Effects of Gastrodia elata and Its Phenolic Constituents in Mice(Pharmacology)
- Zeaxanthin Dipalmitate from Lycium chinense Fruit Reduces Experimentally Induced Hepatic Fibrosis in Rats
- A Novel Cerebroside from Lycii Fructus Preserves the Hepatic Glutathione Redox System in Primary Cultures of Rat Hepatocytes
- Curcumin Suppresses Lipopolysaccharide-Induced Cyclooxygenase-2 Expression by Inhibiting Activator Protein 1 and Nuclear Factor кB Bindings in BV2 Microglial Cells
- Mulberroside F Isolated from the Leaves of Morus alba Inhibits Melanin Biosynthesis
- Protective Effect of Methanol Extract of Uncaria rhynchophylla Against Excitotoxicity Induced by N-Methyl-D-Aspartate in Rat Hippocampus
- Ethyl Acetate Soluble Fraction of Cnidium officinale MAKINO Inhibits Neuronal Cell Death by Reduction of Excessive Nitric Oxide Production in Lipopolysaccharide-Treated Rat Hippocampal Slice Cultures and Microglia Cells
- (4-Methoxy-benzylidene)-(3-methoxy-phenyl)-amine, a Nitrogen Analog of Stilbene as a Potent Inhibitor of Melanin Production
- Geniposide from Gardenia jasminoides Attenuates Neuronal Cell Death in Oxygen and Glucose Deprivation-Exposed Rat Hippocampal Slice Culture(Pharmacognosy)
- A New Caffeoly Quinic Acid from Aster scaber and Its Inhibitory Activity against Human Immunodeficiency Virus-1 (HIV-1) Integrase
- Red Ginseng Inhibits Exercise-Induced Increase in 5-Hydroxytryptamine Synthesis and Tryptophan Hydroxylase Expression in Dorsal Raphe of Rats
- Induction of Nerve Growth Factor by Butanol Fraction of Liriope platyphylla in C6 and Primary Astrocyte Cells(Pharmacognosy)
- アルミナにより表面処理した天然黒鉛の電気化学特性の改善
- Synthesis of MnMoO_4 as High Capacity Anode Material for Li Secondary Battery
- Neuroprotective and Neurotrophic Effects of Quinic Acids from Aster scaber in PC12 Cells
- Effect of Dietary Level of Pectin on Immunoglobulin and Cytokine Production by Mesenteric Lymph Node Lymphocytes and Interleukin-2 Receptor in Rats
- Efficacy of Dietary Aloe vera Supplementation on Hepatic Cholesterol and Oxidative Status in Aged Rats
- Effect of the Flavonoid Components Obtained from Scutellaria Radix on the Histamine, Immunoglobulin E and Lipid Peroxidation of Spleen Lymphocytes of Sprague-dawley Rats(Food & Nutrition Science)
- Synthesis and Application of Neoglycolipids for Liposome Modification
- Hepatic Acumulation of Glutamic Acid Branched Neogalactosyllipid Modified Liposomes
- N-trans-Feruloyltyramine as a Melanin Biosynthesis Inhibitor(Medicinal Chemistry)
- Bis-(2-amino-5-selenazoyl) Ketone as a Superoxide Anion-Scavenger(Medicinal Chemistry)
- Superoxide Anion-Scavenging Effect of 2-Amino-1,3-selenazoles
- Development of a High-Performance Web-Server through a Real-Time Compression Architecture(Internet)
- Software Implementation of a Secure Socket Layer (SSL) Accelerator Based on Kernel Thread
- Network Control and Management for the Next Generation Internet(Special Issue on Advanced Internetworking based on Photonic Network Technologies)
- Two Flavonoids from the Leaves of Mours alba Induce Differentiation of the Human Promyelocytic Leukemia (HL-60) Cell Line
- High Dosage Sildenafil Induces Hearing Impairment in Mice(Miscellaneous)
- Synthesis of Boron-containing CDS-1 Zeolite by Topotactic Dehydration-Condensation of [B]-PLS-1 Prepared from Layered Silicate H-LDS
- Synthesis of 1,3-Selenazines and 1,3-Selenazolidines via Intramolecular Addition of N-Allylselenoureas
- Ginseng radix Increases Cell Proliferation in Dentate Gyrus of Rats with Streptozotocin-Induced Diabetes
- Effect of Dietary Pectin on the Production of Immunoglobulins and Cytokines by Mesenteric Lymph Node Lymphocytes in Mouse Colitis Induced with Dextran Sulfate Sodium(Food & Nutrition Science)
- Wear characteristics of composite resins containing prepolymerized particle fillers
- Dietary Restriction Downregulates Free Radical and Lipid Peroxide Production : Plausible Mechanism for Elongation of Life Span
- Subcutaneous Phaeohyphomycosis caused by Phaeoacremonium rubrigenum in an Immunosuppressed Patient
- Protective Effects of Cinnamomum cassia Blume in the Fibrogenesis of Activated HSC-T6 Cells and Dimethylnitrosamine-Induced Acute Liver Injury in SD Rats
- Inhibitory Effects of Whisky Congeners on Melanogenesis in Mouse B16 Melanoma Cells
- Reaction of Primary Selenoamides with Bisacyl Chlorides: Syntheses of 6 - Hydroxy - 1,3 - selenazin - 4 - ones and Selenoanhydrides
- Preparation of 2-dialkylamino-1,3-selenazoles by reaction of N,N-unsubstituted selenoureas with α-diketones
- Synthesis of 2-Amino-1,3-selenazoles by Reaction of N,N-Unsubstituted Selenoureas with α,β-Unsaturated Aldehydes
- Synthesis of 2-Amino-4,5-dihydro-1,3-selenazol-4-ones by Reaction of N,N-Disubstituted Selenoureas with Acetylenedicarboxylate
- Preparation of 2-Amino-1,3-selenazoles by Reaction of N,N-Unsubstituted Selenoureas with, α,β-Unsaturated Ketones in Alcohol
- Synthesis of 1,3-Selenazetidines and 4H-1,3,5-Oxadiazines Using Acyl Isoselenocyanates
- Synthesis of Selenosemicarbazides and 1,2,4-Triazoles
- Syntheses of 4,5-Dihydroselenophenes by Using TiCl_4 and Zn
- HPLC with pulsed amperometric detection for sorbitol as a biomarker for diabetic neuropathy
- Bioactive Phenolic Constituents from the Seeds of Pharbitis nil
- A Facile Preparation of Aliphatic and Aromatic Primary Selenoamides Using 4-Methylselenobenzoate as a New Selenating Reagent
- Antioxidative Activity and Chemical Constituents of Edible Terrestrial Alga Nostoc commune Vauch.
- Acacetin Protects Dopaminergic Cells against 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Neuroinflammation in Vitro and in Vivo
- Inhibitory Effects of 6-Alkoxycoumarin and 7-Alkoxycoumarin Derivatives on Lipopolysaccharide/Interferon γ-Stimulated Nitric Oxide Production in RAW264 Cells
- Diosgenin from Dioscorea nipponica Ameliorates Diabetic Neuropathy by Inducing Nerve Growth Factor
- Synthesis and Cytotoxicity on Human Leukemia Cells of Furonaphthoquinones Isolated from Tabebuia Plants
- Efficacy of Dietary Aloe vera Supplementation on Hepatic Cholesterol and Oxidative Status in Aged Rats
- Bis(ferrocenecarbothioyl) sulfide. synthesis and characterization.
- A facile preparation of O-alkyl selenocarboxylates and selenoamides via Se-alkynyl selenocarboxylates.
- The Kinetics of the Reaction of Thiol Acids with Anilines