Two Flavonoids from the Leaves of Mours alba Induce Differentiation of the Human Promyelocytic Leukemia (HL-60) Cell Line
スポンサーリンク
概要
- 論文の詳細を見る
Two flavonoids, quercetin-3-O-β-D-glucopyranoside (1) and quercetin-3,7-di-O-β-D-glucopyranoside (2), were isolated from the leaves of Mours alba (Moraceae). These two flavonoids exerted a significant inhibitory effect on the growth of the human promyelocytic leukemia cell line (HL-60) at the concentration of 2×10^<-4> M. Compound 2 also induced differentiation of the HL-60 cell line to express CD 66b and CD 14 antigens. These flavonoids exhibited significant free radical scavenging effects on 1,1-diphenyl-2-picyl-hydrazyl radical.
- 公益社団法人日本薬学会の論文
- 2000-04-01
著者
-
KIM Sun
Graduate School of East-West Medicine, Kyung Hee University
-
GAO Jian
School of Pharmaceutical Science, Beijing Medical University
-
Kang Hee
Cheiju National University Medical School
-
Gao Jian
School Of Pharmaceutical Science Beijing Medical University
-
Kim Sun
Graduate School Of East-westl Medical Science Kyunghee University
-
Kim Sun
Graduate School Of East-west Medical Science East-west Integrated Medical Science Research Center Ky
-
Kim Sun
Graduate School Of East-west Medical Science
関連論文
- Protective Effects of Cinnamomum cassia Blume in the Fibrogenesis of Activated HSC-T6 Cells and Dimethylnitrosamine-Induced Acute Liver Injury in SD Rats
- Regulation of Melanin Synthesis by Selenium-Containing Carbohydrates
- Potent Inhibitory Effects of N-Aryl S-Alkylthiocarbamate Derivatives on the Dopa Oxidase Activity of Mushroom Tyrosinase
- The Effects of PVA/Chitosan/Fibroin (PCF)-Blended Spongy Sheets on Wound Heailng in Rats
- Protective Effect of (4-Methoxybenzylidene)-(3-methoxynophenyl)amine against Neuronal Cell Death Induced by Oxygen and Glucose Deprivation in Rat Organotypic Hippocampal Slice Culture(Medicinal Chemistry)
- Inhibition of Tyrosinase Activity by N, N-Unsubstituted Selenourea Derivatives(Medicinal Chemistry)
- Inhibitory Effects of 1,3-Selenazol-4-one Derivatives on Mushroom Tyrosinase
- High-Dosage Pyridoxine-Induced Auditory Neuropathy and Protection with Coffee in Mice(Pharmacology)
- The Seed Extract of Cassia obtusifolia Ameliorates Learning and Memory Impairments Induced by Scopolamine or Transient Cerebral Hypoperfusion in Mice
- Effects of Anemarrhena asphodeloides on Focal Ischemic Brain Injury Induced by Middle Cerebral Artery Occlusion in Rats(Pharmacology)
- Enhancement of Neuroprotection of Mulberry Leaves (Morus alba L.) Prepared by the Anaerobic Treatment against Ischemic Damage(Pharmacology)
- Zeaxanthin Dipalmitate from Lycium chinense Fruit Reduces Experimentally Induced Hepatic Fibrosis in Rats
- Mulberroside F Isolated from the Leaves of Morus alba Inhibits Melanin Biosynthesis
- (4-Methoxy-benzylidene)-(3-methoxy-phenyl)-amine, a Nitrogen Analog of Stilbene as a Potent Inhibitor of Melanin Production
- Induction of Nerve Growth Factor by Butanol Fraction of Liriope platyphylla in C6 and Primary Astrocyte Cells(Pharmacognosy)
- Neuroprotective and Neurotrophic Effects of Quinic Acids from Aster scaber in PC12 Cells
- Effect of Dietary Level of Pectin on Immunoglobulin and Cytokine Production by Mesenteric Lymph Node Lymphocytes and Interleukin-2 Receptor in Rats
- Efficacy of Dietary Aloe vera Supplementation on Hepatic Cholesterol and Oxidative Status in Aged Rats
- Two Flavonoids from the Leaves of Mours alba Induce Differentiation of the Human Promyelocytic Leukemia (HL-60) Cell Line
- High Dosage Sildenafil Induces Hearing Impairment in Mice(Miscellaneous)
- Protective Effects of Cinnamomum cassia Blume in the Fibrogenesis of Activated HSC-T6 Cells and Dimethylnitrosamine-Induced Acute Liver Injury in SD Rats
- HPLC with pulsed amperometric detection for sorbitol as a biomarker for diabetic neuropathy
- Bioactive Phenolic Constituents from the Seeds of Pharbitis nil
- Acacetin Protects Dopaminergic Cells against 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Neuroinflammation in Vitro and in Vivo
- Diosgenin from Dioscorea nipponica Ameliorates Diabetic Neuropathy by Inducing Nerve Growth Factor
- Efficacy of Dietary Aloe vera Supplementation on Hepatic Cholesterol and Oxidative Status in Aged Rats