Effect of the Flavonoid Components Obtained from Scutellaria Radix on the Histamine, Immunoglobulin E and Lipid Peroxidation of Spleen Lymphocytes of Sprague-dawley Rats(Food & Nutrition Science)
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概要
- 論文の詳細を見る
The effect on the IgE content induced by concanavalin A in spleen lymphocytes of the presence wogonin, ganhuangenin, wogonoside and 3, 5, 7, 2', 6'-pentahydroxyl flavanone was investigated. These flavonoid components markedly inhibited the histamine released from cells stimulated with the calcium ionophore, A23187. However, the magnitude of the inhibitory effect on the degree of lipid peroxidation by ConA of these components was in order of PHF>GHG>WG>WGS. Interestingly, WG, GHG and WGS, with a methoxyl group in the A and B rings, strongly inhibited histamine and IgE production, whereas PHF without a methoxyl group was much stronger than that for lipid peroxidation. We suggest that WG, GHG and WGS might block the pathway for the release of histamine, and that the IgE level in spleen lymphocytes is responsible for the lipid peroxidation.
- 社団法人日本農芸化学会の論文
- 2003-05-23
著者
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Kim Jong
School of Applied Chemical Engineering & The Institute for Catalysis Research, Chonnam National Univ
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Kim Jong
Department Of Surgery College Of Medicine Hallym University
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Lee Bong-hee
Institute For Systems Medicine Gil Medical Center Gachon University Of Medicine And Science
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Lee Bong-hee
韓国
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LIM Beong
Graduate School of East-West Medical Science, Kyung Hee University
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Lim B
Department Of Life Science Konkuk University
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Lim Beong
Graduate School Of East-west Medical Science Kyung Hee University
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Lim Beong
Laboratory Of Food Science Department Of Food Science And Technology Faculty Of Agriculture 46-09 Ky
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LEE Hyeon
School of Biotechnology and Bioengineering, Kangwon National University
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Lim Beong
Department Of Life Science Konkuk University
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SEONG Nak
National Institute of Crop Science
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CHOUE Ryo
Graduate School of East-West Medical Science, Kyung Hee University
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SEONG Nak
Crop Experiment Stations
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Lee Hak
Division Of Wood Chemistry & Microbiology Korea Forest Research Institute
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Choue Ryo
Graduate School Of East-west Medical Science Department Of Medical Nutrition Kyung Hee University:re
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Seong Nak
Crop Experiment Station
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Lee H
College Of Bioscience And Biotechnology Department Of Biomaterials Engineering Kangwon National Univ
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