N-trans-Feruloyltyramine as a Melanin Biosynthesis Inhibitor(Medicinal Chemistry)

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概要

• 論文の詳細を見る

• In this study, we examined the effect of N-trans-feruloyltyramine (FA) on melanogenesis in mouse B16 melanoma cells. Melanogenesis was inhibited by FA in a dose-dependent manner. FA exhibited a greater potency than kojic acid as a standard inhibitor of melanogenesis. Moreover, treatment of B16 melanoma cells with FA was found to cause marked decreases in the expression levels of tyrosinase. FA-induced downregulation of tyrosinase resulted in suppression of melanin biosynthesis in murine B16 melanoma cells.

• 公益社団法人日本薬学会の論文
• 2007-10-01

著者

• Koike Minako

  岐阜県国際バイオ研究所

• Nozawa Yoshinori

  Gifu International Institute of Biotechnology

• Ohguchi Kenji

  Gifu International Institute of Biotechnology

• AKAO Yukihiro

  Gifu International Institute of Biotechnology

• KOKETSU Mamoru

  Division of Instrumental Analysis, Life Science Research Center, Gifu University

• ISHIHARA Hideharu

  Department of Chemistry, Faculty of Engineering, Gifu University

• Akao Y

  Gifu International Institute Of Biotechnology

• Nozawa Y

  Gifu International Institute Of Biotechnology

• Araki Yoko

  Nagaragawa Res. Center Api Co. Ltd.

• Araki Yoko

  Nagaragawa Research Center Api Co. Ltd.

• Koketsu Mamoru

  Division Of Instrumental Analysis Life Science Research Center Gifu University

• EFDI Mai

  Department of Chemistry, Faculty of Engineering, Gifu University

• Efdi Mai

  Department Of Chemistry Faculty Of Engineering Gifu University

• Koketsu Mamoru

  Research Center Suntory Limited

• Ishihara Hideharu

  Department Of Chemistry Faculty Of Engineering Gifu University

• Mamoru Koketsu

  Research Center Suntory Limited

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