Cell Growth Inhibitory Effect of Cinnamic Acid Derivatives from Propolis on Human Tumor Cell Lines

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概要

• 論文の詳細を見る

• A cell growth inhibitory effect of drupanin and baccharin, ingredients of propolis, was found in human cancer cell lines. These compounds induced apoptosis in the cells characterized by morphological and nucleosomal DNA fragmentation analysis. Their effects were less potent compared with that of artepillin C, which is a known anticancer compound from propolis. Importantly, HL60 cells were more sensitive to drupanin than were Con A-stimulated peripheral blood lymphocytes, whereas the potency of artepillin C was the opposite of that of drupanin.

• 公益社団法人日本薬学会の論文
• 2003-07-01

著者

• Nozawa Yoshinori

  Gifu International Institute of Biotechnology

• Murata Hiroko

  東海大学 農学研究科

• Ohguchi Kenji

  Gifu International Institute of Biotechnology

• AKAO Yukihiro

  Gifu International Institute of Biotechnology

• Murata Hiroko

  Faculty Of Pharmaceutical Sciences Setsunan University

• Akao Y

  Gifu International Institute Of Biotechnology

• Nozawa Y

  Gifu International Institute Of Biotechnology

• MATSUMOTO Kenji

  Gifu International Institute of Biotechnology

• Araki Yoko

  Nagaragawa Res. Center Api Co. Ltd.

• Araki Yoko

  Nagaragawa Research Center Api Co. Ltd.

• MARUYAMA Hiroe

  API Company Limited Research Institute

• ARAKI Yoko

  API Company Limited Research Institute

• MISHIMA Satoshi

  API Company Limited Research Institute

• NISHIZAWA Kumi

  Gifu International Institute of Biotechnology

• SAKAMOTO Takashi

  API Company Research Institute

• Haramoto Mari

  Graduate School Of Comprehensive Scientific Research Program In Biological System Sciences Prefectur

• Murata H

  Okayama Univ. Okayama Jpn

• Nishizawa K

  Gifu International Institute Of Biotechnology

• Maruyama Hiroe

  Api Co. Ltd. Nagaragawa Research Center

• Matsumoto K

  Gifu International Institute Of Biotechnology

• Matsumoto Keiji

  Department Of Orthopaedic Surgery Shiga University Of Medical Science

• Mishima Satoshi

  Nagaragawa Research Center Api Co. Ltd.

• Mishima Satoshi

  Api Co. Ltd. Nagaragawa Research Center

• Saito Tetsuya

  Research & Development Center Fuso Pharmaceutical Industries

• Matsumoto K

  Central Research Laboratory Hitachi Ltd.

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