Nitrile Hydratase and Its Application to Industrial Production of Acrylamide
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概要
- 論文の詳細を見る
Nitrile hydratase (NHase) was discovered in our laboratory. This enzyme was purified and characterized from various microorganisms. NHases are roughly classified into two groups according to the metal involved: Fe-type and Co-type. NHases are expected to have great potential as catalysts in organic chemical processing because they can convert nitriles to the corresponding higher-value amides under mild conditions. We have used microbial enzymes for the production of useful compounds; NHase has been used for the industrial production (production capacity: 30,000 tons/year) of acrylamide from acrylonitrile. This is the first successful example of a biotransformation process for the manufacture of a commodity chemical. This review summarizes the history of NHase studied not only from a basic standpoint but also from an applied point of view.
- 社団法人日本農芸化学会の論文
- 1996-09-23
著者
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Kobayashi Michihiko
Department of Agricultural Chemistry, Faculty of Agriculture, Kyoto University
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Kobayashi Michihiko
Department Of Agricultural Chemistry Faculty Of Agriculture Kyoto University
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Yamada Hideaki
Department Of Agricultural Chemistry Faculty Of Agriculture Kyoto University
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