Peanut-Skin Polyphenols, Procyanidin A1 and Epicatechin-(4 β→6)-epicatechin-(2 β→O→7, 4 β→8)-catechin, Exert Cholesterol Micelle-Degrading Activity in Vitro
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概要
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We identified epicatechin-(4 β→6)-epicatechin-(2 β→O→7, 4 β→8)-catechin (EEC) in the skin of the peanut (Arachis hypogaea L.). EEC (a trimer) showed more potent cholesterol micelle-degrading activity than procyanidin A1 (a dimer) did in vitro. The hypercholesterolemia suppressing effect of a peanut skin polyphenol on rats fed high-cholesterol diet in our preceding experiments might thus have been due primarily to a micelle degrading effect in the intestine.
著者
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KOSHINO Hiroyuki
RIKEN
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Inoue Naoko
Department Of Life Science Faculty Of Science Himeji Of Technology
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Tamura Tomoko
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences Univers
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SHIMIZU-IBUKA Akiko
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The U
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Abe Naoki
Department Of Agricultural Chemistry Faculty Of Agriculture Tohoku University
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Mura Kiyoshi
Department Of Nutritional Science Faculty Of Applied Bioscience Tokyo University Of Agriculture
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Tamura Tomoko
Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture
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ARAI Soichi
Department of Agricultural Chemicatry, The University of Tokyo
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INOUE Naoko
Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture
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OZAWA Megumi
Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture
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KOSHINO Hiroyuki
RIKEN Advanced Science Institute
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