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Between July, 1972 and May, 1982, we treated 151 patients with hepatocellular carcinoma (HCC) using various treatments at Kitasato University Hospital. Of this series, all had undergone angiography before initial treatment and then their cilinical follow-up studies were made sufficiently. Angiographically, the presence of HCC was delineated in all patients. The methods of treatment were divided into the following four groups: (1) conservative measure including systemic chemotherapy, (2) intraarterial injection chemotherapy, (3) transcatheter arterial embolization and (4) surgical treatment. Among these groups, comparison was made justifiably using a staging system proposed by us, which consists of both morphological and functional classifications. The results of each treatment and the prognosis for HCC following treatment were reviewed and discussed in order to accurately predict the effect of treatment and to properly choose the methods of treatment at the time of patients selection for the management of HCC.The conclusions were as follows: (1) In the absence of coexisting liver cirrhosis, patients with HCC classified into Type A morphologically should be initially treated surgically because complete cure can be only expected with hepatic resection at the present time. (2) In the presence of coexisting liver cirrhosis, on the other hand, it is recommended that patients with HCC classified into Type A and B morphologically should be treated with transcatheter arterial embolization instead of surgical treatment because the survival rate of the former is superior to that of the latter and a surgical mortality rate in 20 resected cases of this series remains as high as 20%.
財団法人日本消化器病学会の論文

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