EFFECT OF STIMULATION OF LOCUS COERULEUS ON THE EVOKED POTENTIAL IN THE AMYGDALA IN RATS
スポンサーリンク
概要
- 論文の詳細を見る
Effects of stimulation of the locus coeruleus (LC) on evoked potential in the medial amygdala elicited by stimulation of the olfactory bulb (OB-AME potential) were studied in gallamine-immobilized rats. The amplitude of the OB-AME potential was inhibited 27.5%. by the conditioning stimulation of LC delivered 30 msec before the test stimulation. The inhibitory effect of LC was reduced by propranolol 5 mg/kg i.p., but not by phentolamine 10 mg/kg i.p.. This effect was also reduced by tetrabenazine 10 mg/kg i.p.. Methamphetamine 5 mg/kg i.p. produced considerable potentiation of the LC inhibitory effect and a reduction of the OB-AME potential itself. These results suggest that the LC plays an inhibitory role in the electrical activity of the medial amygdala.
- 社団法人 日本薬理学会の論文
著者
-
Oishi Ryozo
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University
-
Ohmori Kenji
Pharmaceutical Research Institute Kyowa Hakko Kogyo Co. Ltd.
-
Ueki Showa
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyushu University
-
Watanabe Shigenori
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyushu University
-
Shibata Shigenobu
Department Of Pharmacology School Of Human Sciences Waseda University
-
Shibata Shigenobu
Department Of Pharmacology Faculty Of Human Sciences Waseda University
-
OHMORI Kenji
Pharmaceutical Research Laboratory, Kyowa Hakko Kogyo Co. Ltd.
-
OISHI Ryozo
Department of Pharmacology, Faculty of Medicine, Kyushu University
-
UEKI Showa
Department of Phamacology, Faculty of Pharmaceutical Sciences, Kyushu University
関連論文
- Neuroprotective Effect of Repeated Treatment with Hericium erinaceum in Mice Subjected to Middle Cerebral Artery Occlusion
- Delta(9)-tetrahydrocannabinol Enhances an Increase of Plasma Corticosterone Levels Induced by Forced Swim-Stress
- New Topics in Vasopressin Receptors and Approach to Novel Drugs : Role of the Vasopressin Receptor in Psychological and Cognitive Functions
- Growth Processes and Electrical Characteristics of Silicon Nitride Films Formed on Si(100) by Radical Nitrogen
- Neuroprotective Effects of Kangen-karyu on Spatial Memory Impairment in an 8-Arm Radial Maze and Neuronal Death in the Hippocampal CA1 Region Induced by Repeated Cerebral Ischemia in Rats
- Characteristics of Gabexate Mesilate–Induced Cell Injury in Porcine Aorta Endothelial Cells
- Calcium-Channel Antagonists Inhibit Marble-Burying Behavior in Mice
- New Approach for Measurement of Sympathetic Nervous Abnormality in Conscious, Spontaneously Hypertensive Rats
- 2,5-Dimethoxy-4-iodoamphetamine (DOI) Inhibits Δ^9-Tetrahydrocannabinol-Induced Catalepsy-Like Immobilization in Mice
- Evaluation of Effectiveness of New Infusion Set Equipped with an In-line Filter
- REVIEW : New Drug and Recent Technique : Pharmacological, Pharmacokinetic and Clinical Properties of Olopatadine Hydrochloride, a New Antiallergic Drug
- Effects of olopatadine hydrochloride on the release of thromboxane B_2 and histamine from nasal mucosa after antigen-antibody reaction in guinea pigs
- Effects of Olopatadine Hydrochloride on the Cutaneous Vascular Hyperpermeability and the Scratching Behavior Induced by Poly-_L-Arginine in Rats
- Inhibitory Effect of Olopatadine Hydrochloride on the Sneezing Response Induced by Intranasal Capsaicin Challenge in Guinea Pigs
- Involvement of Neuropeptides in the Allergic Nasal Obstruction in Guinea Pigs
- Inhibitory effect of olopatadine hydrochloride (KW-4679), a novel antiallergic drug, on peptide leukotriene release from human eosinophils
- Possible Involvement of 5-HT_4 Receptors, in Addition to 5-HT_3 Receptors, in the Emesis Induced by High-Dose Cisplatin in Suncus murinus
- The Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Acetylcholine-Induced Intestinal Electrolyte Secretion
- Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16, 16-Dimethyl Prostaglandin E_2-Induced Intestinal Ion Secretion in Rats
- Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca^-Mediated Short-Circuit Current Response in the Rat Colonic Mucosa
- Effect of Oxatomide on Experimental Allergic Rhinitis in Guinea Pigs
- Comparison of the Antidiarrheal Effects of Zaldaride Maleate and Its Optical Isomers in Rats
- Gender Differences in the Antidiarrheal Effect of Zaldaride Maleate in Rats
- Antidiarrheal Effects of Zaldaride Maleate After Oral, Intravenous and Subcutaneous Administration to Rats
- Determination of salicylic acid in human serum with capillary zone electrophoresis
- Clinical and Experimental Evidence for Prevention of Acute Renal Failure Induced by Radiographic Contrast Media
- Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs) : Role of Tryptase/PAR-2 in Vascular Endothelial Barrier Function
- Nafamostat Mesilate Is an Extremely Potent Inhibitor of Human Tryptase
- Involvement of the Medial Amygdaloid Nucleus in the Action of Imipramine in Rats Subjected to the Forced Swimming Test
- A NEW FORCED SWIMMING TEST FOR THE EVALUATION OF ANTIDEPRESSANTS IN RATS BY RECORDING VIBRATION OF A WATER TANK
- Potentiation of _L-Dopa-Induced Behavioral Excitement by Histamine H_1-Receptor Antagonists in Mice
- EFFECTS OF LIMBIC LESIONS, ESPECIALLY OF OLFACTORY BULBECTOMY ON SIMPLE CONDITIONED AVOIDANCE RESPONSE IN RATS
- Effect of KW-4679, an Orally Active Anti-allergic Drug, on Antigen-Induced Airway Hyperresponsiveness in Actively Sensitized Guinea Pigs
- Growth Processes and Electrical Characteristics of Silicon Nitride Films Formed on Si(100) by Radical Nitrogen
- Microscopic Observation of X-Ray Irradiation Damages in Ultra-Thin SiO_2 Films
- Oxide Formation on Si(100)-2×1 Surfaces Studied by Scanning Tunneling Microscopy/Scanning Tunneling Spectroscopy
- Study on Oxidation of Si(100)-2x1 Surfaces by Scanning Tunneling Microscopy/Scanning Tunneling Spectroscopy
- Yokukansan Inhibits Social Isolation-Induced Aggression and Methamphetamine-Induced Hyperlocomotion in Rodents(Pharmacology)
- Involvement of GABA_A Receptors in the Neuroprotective Effect of Theanine on Focal Cerebral Ischemia in Mice
- Enantioselective determination of thiamylal in human serum by high-performance liquid chromatography
- PHARMACOLOGICAL CHARACTERISTICS OF ABNORMAL BEHAVIOR INDUCED BY HARMINE WITH SPECIAL REFERENCE TO TREMOR IN MICE
- Inhibitory Effect of KW-4679, an Anti-allergic Drug, on Tachykinin-Mediated Airway Response Induced by Electric Vagal Stimulation in Guinea Pigs
- Biochemical and Pharmacological Properties of 5-Lipoxygenase Inhibitor KF8940(Biological Chemistry)
- Application of high-performance thin-layer chromatography for the detection of organophosphorus insecticides in human serum after acute poisoning
- Micellar electrokinetic capillary chromatography for therapeutic drug monitoring of zonisamide
- Enhancement by Morphine of Radiographic Contrast Media-Induced Histamine Release in Rat Peritoneal Mast Cells
- Protective Effects of Amino Acids Against Gabexate Mesilate-Induced Cell Injury in Porcine Aorta Endothelial Cells
- Characteristics of Gabexate Mesilate-Induced Cell Injury in Porcine Aorta Endothelial Cells
- In Vivo Evidence for a Lack of Central Effect of Ebastine, an Antihistaminic Agent, in Rats : a Microdialysis Study
- A Key Role of the Mammillary Body in Mediation of the Antianxiety Action of Zopiclone, a Cyclopyrrolone Derivative
- Ameliorating effects of Kangen-karyu on neuronal damage in rats subjected to repeated cerebral ischemia
- Yokukansan Enhances Pentobarbital-Induced Sleep in Socially Isolated Mice: Possible Involvement of GABAA – Benzodiazepine Receptor Complex
- THE EFFECT OF AGE ON THE DEVELOPMENT OF HYPEREMOTIONALITY FOLLOWING BILATERAL OLFACTORY BULBECTOMY IN RATS
- Mexiletine Reverses Oxaliplatin-Induced Neuropathic Pain in Rats
- THE ROLE OF NORADRENERGIC AND SEROTONERGIC SYSTEMS IN THE HIPPOCAMPAL KINDLING EFFECT
- EFFECTS OF RESERPINE, α-METHYL-p-TYROSINE, P-CHLOROPHENYLALANINE AND 5, 7-DIHYDROXYTRYPTAMINE ON THE HIPPOCAMPAL KINDLING EFFECT IN RATS
- EFFECTS OF DELTA-9-TETRAHYDROCANNABINOL ON THE CARDIOVASCULAR SYSTEM, AND PRESSOR AND BEHAVIORAL RESPONSES TO BRAIN STIMULATION IN RATS
- CARDIOVASCULAR CHANGES INDUCED BY LARGE DOSES OF CLONIDINE IN MICE
- Rapid and sensitive detection of benzodiazepines and zopiclone in serum using high-performance thin-layer chromatography
- Comparison of Peripheral Neuropathy Induced by Standard and Nanoparticle Albumin–Bound Paclitaxel in Rats
- Comparison of Injuring Effects of Vesicant, Irritant, and Nonvesicant Anticancer Drugs on Endothelial Cells
- Behavioral and Electroencephalographic Effects of a Depot Type Neuroleptic Fluphenazine Decanoate, in Rats
- CENTRAL CHOLINERGIC ACTIVATION BY CHLORFEN VINPHOS, AN ORGANOPHOSPHATE, IN THE RAT
- EFFECT OF ZOTEPINE ON HEAD-TWITCH INDUCED BY L-5-HYDROXYTRYPTOPHAN, MESCALINE AND 2, 5-DIMETHOXY-4-METHYLAMPHETAMINE IN MICE AND RATS
- EFFECTS OF LOCUS COERULEUS STIMULATION ON MURICIDE IN OLFACTORY BULBECTOMIZED AND RAPHE LESIONED RATS
- EFFECT OF AMINO ACIDS AND MONOAMINES ON THE NEURONAL ACTIVITY OF SUPRACHIASMATIC NUCLEUS IN HYPOTHALAMIC SLICE PREPARATIONS
- EFFECTS OF PSYCHOTROPIC DRUGS INJECTED INTO THE LIMBIC STRUCTURES ON MOUSE-KILLING BEHAVIOR IN THE RAT WITH OLFACTORY BULB ABLATIONS
- EFFECTS OF ELECTROCONVULSIVE SHOCK ON MOUSE-KILLING BEHAVIOR (MURICIDE) IN OLFACTORY BULBECTOMIZED RATS
- EFFECT OF DESIPRAMINE ON NORADRENERGIC INHIBITION OF AMYGDALOID EVOKED POTENTIAL
- EFFECT OF STIMULATION OF LOCUS COERULEUS ON THE EVOKED POTENTIAL IN THE AMYGDALA IN RATS
- THE ROLE OF THE LOCUS COERULEUS IN REGULATION OF SEIZURE SUSCEPTIBILITY IN RATS
- INFLUENCE OF AGGREGATION ON THE ACTION OF METHAMPHETAMINE IN LOCOMOTOR ACTIVITY
- POSSIBLE INVOLVEMENT OF A CENTRAL NORADRENERGIC SYSTEM IN AUTOMUTILATION INDUCED BY CLONIDINE IN MICE
- CHANGES IN SENSITIVITY OF MICE TO ANTICONVULSANT DRUGS FOLLOWING BILATERAL OLFACTORY BULB ABLATIONS
- EFFECTS OF MONOAMINES INJECTED INTO THE HIPPOCAMPUS ON HIPPOCAMPAL SEIZURE DISCHARGES IN THE RABBIT
- EFFECT OF MEDIAN RAPHE STIMULATION ON HIPPOCAMPAL SEIZURE DISCHARGE INDUCED BY CARBACHOL IN THE RABBIT
- CHANGES IN SENSITIVITY TO CONVULSION IN MICE WITH OLFACTORY BULB ABLATION
- EFFECT OF SODIUM DIPROPYLACETATE ON CONFLICT BEHAVIOR IN RATS
- EFFECT OF L-5HTP ON TREMORINE- OR OXOTREMORINE- INDUCED TREMOR IN MICE AND RATS
- SIGNIFICANCE OF WITHDRAWAL JUMPING RESPONSE IN PREDICTING PHYSICAL DEPENDENCE IN MICE
- NALOXONE-INDUCED ABSTINENCE SYNDROMES IN MORPHINE-TREATED MICE
- Yokukansan Enhances Pentobarbital-Induced Sleep in Socially Isolated Mice : Possible Involvement of GABA_A-Benzodiazepine Receptor Complex
- Comparison of Injuring Effects of Vesicant, Irritant, and Nonvesicant Anticancer Drugs on Endothelial Cells
- Comparison of Peripheral Neuropathy Induced by Standard and Nanoparticle Albumin-Bound Paclitaxel in Rats
- EFFECTS OF PSYCHOTROPIC DRUGS ON HYPEREMOTION-ALITY OF RATS WITH BILATERAL ABLATIONS OF THE OLFACTORY BULBS AND OLFACTORY TUBERCLES
- HYPEREMOTIONALITY INDUCED BY LESIONS IN THE OLFACTORY SYSTEM OF THE RAT
- Repeated Administration of Amitriptyline Reduces Oxaliplatin-Induced Mechanical Allodynia in Rats
- Role of 5-Hydroxytryptamine2C Receptors in Marble-Burying Behavior in Mice
- N-Acetyl-L-Cysteine Inhibits Marble-Burying Behavior in Mice
- Decrease in Venous Irritation by Adjusting the Concentration of Injected Bendamustine
- Effect of microinjection of histamine into the brain on plasma levels of epinephrine and glucose in freely moving rats.
- Effects of isofloxythepin on central and peripheral histamine systems.
- Effectiveness and Safety of Antiemetic Aprepitant in Japanese Patients Receiving High-Dose Chemotherapy Prior to Autologous Hematopoietic Stem Cell Transplantation
- Effect of a New Psychoactive Compound, MCI-225, on Brain Monoamine Metabolism in Rats.
- Protective Effects of Amino Acids Against Gabexate Mesilate-Induced Cell Injury in Porcine Aorta Endothelial Cells
- Effect of acute treatment of mice with L-histidine on the brain levels of amino acids.
- Histamine turnover in the rat hypothalamic nuclei estimated from .ALPHA.-fluoromethylhistidine-induced histamine decrease.
- 9-Amino-1,2,3,4-Tetrahydroacridine Is a Potent Inhibitor of Histamine N-Methyltransferase.
- Effects of nociceptive stimuli on brain histamine dynamics.
- Effects of GABA-mimetic drugs on turnover of histamine in the mouse brain.