EFFECT OF ZOTEPINE ON HEAD-TWITCH INDUCED BY L-5-HYDROXYTRYPTOPHAN, MESCALINE AND 2, 5-DIMETHOXY-4-METHYLAMPHETAMINE IN MICE AND RATS
スポンサーリンク
概要
- 論文の詳細を見る
The effect of zotepine, a new neuroleptic, on head-twitch induced by L-5-hydroxytryptophan (L-5HTP), mescaline and 2, 5-dimethoxy-4-methylamphetamine (DOM) in mice and rats was compared with that of known neuroleptics and the serotonin receptor blocker cyproheptadine. Among the neuroleptics tested, zotepine and haloperidol produced potent inhibitory effects on head-twitch induced by these three drugs. The results indicate that zotepine has a potent anti-hallucinogenic effect.
- 社団法人 日本薬理学会の論文
著者
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Ueki Showa
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyushu University
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Yamamoto Tsuneyuki
Department Of Developmental Biology Of Hard Tissue Graduate School Of Dental Medicine Hokkaido Unive
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SATOH Hisashi
Research Laboratories, Fujisawa Pharmaceutical Co. Ltd.
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SHIMOMURA Kyoichi
Research Laboratories, Fujisawa Pharmaceutical Co. Ltd.
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MORI Jo
Research Laboratories, Fujisawa Pharmaceutical Co. Ltd.
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TAZOE Naoe
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kyushu University
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UEKI Showa
Department of Phamacology, Faculty of Pharmaceutical Sciences, Kyushu University
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