Hematological Change in Venous Blood of the Lower Leg during Prolonged Sitting in a Low Humidity and Hypobaric Environment

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概要

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• The present study examined the effects of low humidity and hypobaric conditions on hematological change in venous blood of the lower leg during quiet prolonged sitting. Ten healthy male students participated as the subjects after singing a consent form to participate in this study. Their diet and water intake were controlled from 19:00 on the day before the experiments. The subjects sat for 130 min in a climatic chamber. Four experimental conditions in the chamber were designed from a combination of relative humidity (20% or 60%) and air pressure (sea level or equivalent to an altitude of 2,000m). Ambient temperature was maintained at 24℃ in every condition. Venous blood was sampled from the lower leg before and after exposure to the experimental conditions, and was analyzed for blood viscosity and hematological indices. Also, body weight and leg circumference were measured as indices of total water loss and edema, respectively. Regarding the results of ANOVA, significant interactions between humidity and time were observed in blood viscosity, red blood cell count and hematocrit (each p<0.05). However, there were no significant differences in these indices among the conditions. Significant increases were observed in leg circumference (p<0.01), platelet count (p<0.05) and total protein (p<0.05) after the exposure compared with those before the exposure. There were no noticeable effects of hypobaric conditions in every measurement. In conclusion, prolonged sitting seems to be a more hazardous factor for thrombogenesis low humidity and hypobaric conditions during a long-distance flight.

• 日本生理人類学会の論文

著者

• YAMAMOTO Tsuneyuki

  Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University

• TOCHIHARA Yutaka

  Department of Ergonomics, Kyushu University

• Yamamoto Tsuneyuki

  Graduate School Of Design Kyushu University

• Yamashita Kazuaki

  Department of Ergonomics, Faculty of Design, Kyushu University

• Yamaguchi Katsuki

  Department of Ergonomics, Kyushu Institute of Design

• Shirabe Shuntaro

  Department of Ergonomics, Faculty of Design, Kyushu University

• Hashiguchi Nobuko

  Department of Ergonomics, Faculty of Design, Kyushu University

• Kaji Masahide

  Kurume University Medical Center, Center for Rheumatic Disease

• SHIRABE Shuntaro

  Faculty of Design, Kyushu University

• Tochihara Yutaka

  Department Of Ergonomics Faculty Of Design Kyushu University

• Tochihara Yutaka

  Faculty Of Design Kyushu University

• Tochihara Yutaka

  Department Of Physiological Hygiene National Institute Of Public Health

• Kaji Masahide

  Kurume University Medical Center

• Tochihara Yutaka

  Dep. Of Ergonomics Fac. Of Design Kyushu Univ.

• Yamamoto Tsuneyuki

  Department Of Developmental Biology Of Hard Tissue Graduate School Of Dental Medicine Hokkaido Unive

• Shirabe Shuntaro

  Faculty Of Design Kyushu University

• Shirabe Shuntaro

  Department Of Ergonomics Kyushu University

• Hashiguchi Nobuko

  九州大学 芸術工学部人間工学

• Hashiguchi Nobuko

  Department Of Ergonomics Faculty Of Deign Kyushu University

• Yamashita Kazuaki

  Faculty Of Design Kyushu University

• Yamashita Kazuaki

  Department Of Ergonomics Kyushu Institute Of Design

• Tochihara Yutaka

  Department Of Ergonomics Faculty Of Deign Kyushu University

• YAMAMOTO Tsuneyuki

  Graduate School of Design, Kyushu University

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