Involvement of the Medial Amygdaloid Nucleus in the Action of Imipramine in Rats Subjected to the Forced Swimming Test
スポンサーリンク
概要
- 論文の詳細を見る
A forced swimming test proposed by Porsolt is a useful method for screening antidepressants. To evaluate drug effects more objectively, vibration of the walls of a water tank caused by the escape behavior of the rat was recorded. Imipramine (IMI) increased the number of vibration and this effect was observed in the medial amygdala lesioned rat but not in the central or basolateral amygdala lesioned rat. The present result suggests that the medial amygdala is an important site of action of IMI.
- 公益社団法人日本薬学会の論文
著者
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Shimazoe T
Kyushyu Univ. Fukuoka Jpn
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Shimazoe Takao
東京都老人総合研究所
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Shimazoe Takao
Department Of Clinical Physiology Tokyo Metropolitan Institute Of Gerontology
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SHIBATA Shigenobu
Department of Pharmacology, Faculty of Human Sciences, Waseda University
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Shimazoe Takao
The Department Of Pharmacology Graduate School Of Pharmaceutical Science Kyushu University
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YATSUGI Shinichi
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kyushu University
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UEKI Showa
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kyushu University
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Ueki S
Kyushu Univ. Fukuoka Jpn
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Ueki Showa
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyushu University
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Yatsugi Shinichi
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyushu University
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Shibata S
Department Of Pharmacology Faculty Of Human Sciences Waseda University
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Shibata Shigenobu
Department Of Pharmacology School Of Human Sciences Waseda University
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Shibata Shigenobu
Department Of Pharmacology Faculty Of Human Sciences Waseda University
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UEKI Showa
Department of Phamacology, Faculty of Pharmaceutical Sciences, Kyushu University
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