EFFECTS OF LIMBIC LESIONS, ESPECIALLY OF OLFACTORY BULBECTOMY ON SIMPLE CONDITIONED AVOIDANCE RESPONSE IN RATS
スポンサーリンク
概要
- 論文の詳細を見る
Effects of olfactory bulbectomy, and lesions of the septum and dorsal hippocampus on emotionality as well as on the simple conditioned avoidance response in a two-way shuttle box were investigated in rats. The rats with bilateral olfactory bulbectomy (O.B. rats) showed hyperactivity and aggressive behavior, including mouse-killing behavior (muricide), and those with septal lesions exhibited hyperreactivity and hypoactivity, while the rats with hippocampal lesions became hypoactive without showing hyperreactivity. The O.B. and septal rats, on an average, showed a facilitation in acquisition of the conditioned avoidance response and a retardation in extinction. The muricidal group of O.B. rats, however, showed slower acquisition, while the nonmuricidal O.B. rats showed much faster acquisition and slower extinction than intact rats. Hippocampal lesions retarded acquisition.
著者
-
Gomita Yutaka
Department Of Hospital Pharmacy
-
Gomita Yutaka
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyushu University
-
Ueki Showa
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyushu University
関連論文
- Nicotinic Acetylcholine α4β2 Receptor Regulates the Motivational Effect of Intracranial Self Stimulation Behavior in the Runway Method
- Effect of Methamphetamine and Imipramine on Cerebral Ischemia-Induced Hyperactivity in Mongolian Gerbils
- ESTABLISHMENT OF NEUROTRANSMITTER-HYPERSENSITIVE PC12 VARIANT CELLS DEFICIENT IN NERVE GROWTH FACTOR-INDUCED NEURITE OUTGROWTH
- Immunosuppressant FK506 Induces Sustained Activation of MAP Kinase and Promotes Neurite Outgrowth in PC12 Mutant Cells Incapable of Differentiating
- Counseling of Patients with Bronchial Asthma, and Clinical Pharmacy Practice and Education of Pharmacy School Students
- Development and Application of a Cocaine-Selective Electrode (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
- Effect of Diazepam on the Runway Method Using Priming Stimulation of Intracranial Self Stimulation Behavior
- The 5-HT_ Receptor Full Agonist, 8-OH-DPAT Inhibits ACTH-Induced 5-HT_ Receptor Hyperfunction in Rats : Involvement of 5-HT_ Receptors in the DOI-Induced Wet-Dog Shakes in ACTH-Treated Rats(Pharmacology)
- Increased DOI-Induced Wet-Dog Shakes in Adrenocorticotropic Hormone-Treated Rats Are Not Affected by Chronic Imipramine Treatment : Possible Involvement of Enhanced 5-HT_-Receptor Expression in the Frontal Cortex
- Influence of Lactation on Plasma Phenobarbital Concentrations in Rats
- Pharmacokinetics of slow-release preparations of sodium valproate
- Simple and rapid analysis of lamotrigine, a novel antiepileptic, in human serum by high-performance liquid chromatography using a solid-phase extraction technique
- Pharmacokinetics of slow-release preparations of sodium valproate
- Neuronal Nicoticic Receptor and Psychiatric Disorders: Functional and Behavioral Effects of Nicotine
- Motivational Effect of Nomifensine in the Intracranial Self-Stimulation Behavior Using a Runway Method(Pharmacology)
- Selegilin Exerts Antidepressant-Like Effects During the Forced Swim Test in Adrenocorticotropic Hormone-Treated Rats
- Motivational Effects of Methamphetamine as Measured by the Runway Method Using Priming Stimulation of Intracranial Self-stimulation Behavior(Analytical Biochemistry)
- Effects of Imipramine and Bupropion on the Duration of Immobility of ACTH-Treated Rats in the Forced Swim Test : Involvement of the Expression of 5-HT_ Receptor mRNA(Pharmacology)
- Modulation of 8-OH-DPAT-Induced Hypothermia by Imipramine in Rats
- Effects of Long-Term Treatment With Calcium Antagonists on Periarterial Nerve Function in the Mesenteric Artery of Spontaneously Hyupertensive Rats
- Long-Term Treatment With Angiotensin Converting Enzyme Inhibitor Restores Reduced Calcitonin Gene-Related Peptide-Containing Vasodilator Nerve Function in Mesenteric Artery of Spontaneously Hypertensive Rats
- CHANGES IN CIRCADIAN RHYTHM OF LOCOMOTOR ACTIVITY INDUCED BY CEREBRAL ISCHEMIA IN MONGOLIAN GERBILS
- EFFECTS OF CLOBAZAM ON AMYGDALOID AND HIPPOCAMPAL KINDLED SEIZURES IN RATS
- Effects of Chronic Administration of Sibutramine on Body Weight, Food Intake and Motor Activity in Neonatally Monosodium Glutamate-Treated Obese Female Rats: Relationship of Antiobesity Effect with Monoamines
- Effect of Dopaminergic Drugs on the Reserpine-Induced Lowering of Hippocampal Theta Wave Frequency in Rats
- Examination of Particulate Contamination after Opening Ampoules : Relationship between Ampoule Inner-diameter and Glass Particle Accumulation after Opening Ampoules
- Involvement of the Medial Amygdaloid Nucleus in the Action of Imipramine in Rats Subjected to the Forced Swimming Test
- A NEW FORCED SWIMMING TEST FOR THE EVALUATION OF ANTIDEPRESSANTS IN RATS BY RECORDING VIBRATION OF A WATER TANK
- Potentiation of _L-Dopa-Induced Behavioral Excitement by Histamine H_1-Receptor Antagonists in Mice
- EFFECTS OF LIMBIC LESIONS, ESPECIALLY OF OLFACTORY BULBECTOMY ON SIMPLE CONDITIONED AVOIDANCE RESPONSE IN RATS
- PHARMACOLOGICAL CHARACTERISTICS OF ABNORMAL BEHAVIOR INDUCED BY HARMINE WITH SPECIAL REFERENCE TO TREMOR IN MICE
- A Key Role of the Mammillary Body in Mediation of the Antianxiety Action of Zopiclone, a Cyclopyrrolone Derivative
- THE EFFECT OF AGE ON THE DEVELOPMENT OF HYPEREMOTIONALITY FOLLOWING BILATERAL OLFACTORY BULBECTOMY IN RATS
- THE ROLE OF NORADRENERGIC AND SEROTONERGIC SYSTEMS IN THE HIPPOCAMPAL KINDLING EFFECT
- EFFECTS OF RESERPINE, α-METHYL-p-TYROSINE, P-CHLOROPHENYLALANINE AND 5, 7-DIHYDROXYTRYPTAMINE ON THE HIPPOCAMPAL KINDLING EFFECT IN RATS
- EFFECTS OF DELTA-9-TETRAHYDROCANNABINOL ON THE CARDIOVASCULAR SYSTEM, AND PRESSOR AND BEHAVIORAL RESPONSES TO BRAIN STIMULATION IN RATS
- CARDIOVASCULAR CHANGES INDUCED BY LARGE DOSES OF CLONIDINE IN MICE
- Behavioral and Electroencephalographic Effects of a Depot Type Neuroleptic Fluphenazine Decanoate, in Rats
- EFFECTS OF BENZODIAZEPINES ON LOW RATE RESPONDING FOR LOW CURRENT BRAIN STIMULATION REWARDS
- EFFECT OF ZOTEPINE ON HEAD-TWITCH INDUCED BY L-5-HYDROXYTRYPTOPHAN, MESCALINE AND 2, 5-DIMETHOXY-4-METHYLAMPHETAMINE IN MICE AND RATS
- EFFECTS OF LOCUS COERULEUS STIMULATION ON MURICIDE IN OLFACTORY BULBECTOMIZED AND RAPHE LESIONED RATS
- EFFECT OF AMINO ACIDS AND MONOAMINES ON THE NEURONAL ACTIVITY OF SUPRACHIASMATIC NUCLEUS IN HYPOTHALAMIC SLICE PREPARATIONS
- EFFECTS OF PSYCHOTROPIC DRUGS INJECTED INTO THE LIMBIC STRUCTURES ON MOUSE-KILLING BEHAVIOR IN THE RAT WITH OLFACTORY BULB ABLATIONS
- EFFECTS OF ELECTROCONVULSIVE SHOCK ON MOUSE-KILLING BEHAVIOR (MURICIDE) IN OLFACTORY BULBECTOMIZED RATS
- EFFECT OF DESIPRAMINE ON NORADRENERGIC INHIBITION OF AMYGDALOID EVOKED POTENTIAL
- EFFECT OF STIMULATION OF LOCUS COERULEUS ON THE EVOKED POTENTIAL IN THE AMYGDALA IN RATS
- THE EMOTIONAL COMMUNICATION BASED ON METHAMPHETAMINE MORTALITY AS THE INDEX IN OLFACTORY BULBECTOMIZED MICE
- INFLUENCE OF AGGREGATION ON THE ACTION OF METHAMPHETAMINE IN LOCOMOTOR ACTIVITY
- POSSIBLE INVOLVEMENT OF A CENTRAL NORADRENERGIC SYSTEM IN AUTOMUTILATION INDUCED BY CLONIDINE IN MICE
- CHANGES IN SENSITIVITY OF MICE TO ANTICONVULSANT DRUGS FOLLOWING BILATERAL OLFACTORY BULB ABLATIONS
- EFFECTS OF MONOAMINES INJECTED INTO THE HIPPOCAMPUS ON HIPPOCAMPAL SEIZURE DISCHARGES IN THE RABBIT
- EFFECT OF MEDIAN RAPHE STIMULATION ON HIPPOCAMPAL SEIZURE DISCHARGE INDUCED BY CARBACHOL IN THE RABBIT
- CHANGES IN SENSITIVITY TO CONVULSION IN MICE WITH OLFACTORY BULB ABLATION
- SIGNIFICANCE OF WITHDRAWAL JUMPING RESPONSE IN PREDICTING PHYSICAL DEPENDENCE IN MICE
- NALOXONE-INDUCED ABSTINENCE SYNDROMES IN MORPHINE-TREATED MICE
- Differential Effects of Morphine on Operant Escape Behavior and Averse Symptom Induced by Dorsal Central Gray Stimulation in Rats
- EFFECTS OF PSYCHOTROPIC DRUGS ON HYPEREMOTION-ALITY OF RATS WITH BILATERAL ABLATIONS OF THE OLFACTORY BULBS AND OLFACTORY TUBERCLES
- HYPEREMOTIONALITY INDUCED BY LESIONS IN THE OLFACTORY SYSTEM OF THE RAT
- A New Method for Studying Working Memory by Using the Three-Panel Runway Apparatus in Rats
- Involvement of Dopaminergic Receptor Signaling in the Effects of Glutamatergic Receptor Antagonists on Conditioned Place Aversion Induced by Naloxone in Single-Dose Morphine-Treated Rats
- Effects of cholinergic drugs on aversive operant behavior induced by dorsal central gray stimulation in rats.
- Behavioral analysis of zopiclone on the basis of their discriminative stimulus properties in the rat.
- Behavioral effects of HR-592, a new derivative of indole.
- Evaluation of the neuroprotective action of WEB 1881 FU on hypoglycemia/hypoxia-induced neuronal damage using rat striatal slices.
- Behavioral and electroencephalographic effects of zopiclone, a cyclopyrrolone derivative.
- .BETA.-CCM inhibits muricide induced by olfactory bulbectomy in rats.
- WEB 1881 FU ameliorates impairement of working memory induced by scopolamine and cerebral ischemia in the three-panel runway task.
- Role of the amygdala in the hippocampal kindling effect of rats.
- Auto-titration technique using intracranial self-stimulation and effects of antianxiety drugs.
- Neural systems activated by the aversive stimulation of dorsal central gray.
- Effects of methamphetamine on regional cerebral glucose utilization in rats with unilateral lesion of substantia nigra.
- Influence of electric foot shock on pharmacokinetics of isosorbide dinitrate subcutaneously administered to rats.
- Influence of electric foot shock on pharmacokinetics of isosorbide dinitrate orally administered to rats.