Differential Effects of Morphine on Operant Escape Behavior and Averse Symptom Induced by Dorsal Central Gray Stimulation in Rats
スポンサーリンク
概要
- 論文の詳細を見る
The involvement of a central opiate mechanism in the operant escape behavior induced by dorsal central gray (DCG) stimulation was investigated in rats. Morphine (2-10 mg/kg, i.p.) produced a rise in the DCG-stimulation threshold, but did not suppress rapid running as an averse symptom. Naloxone alone affected neither the threshold nor the averse symptom. Nevertheless, naloxone counteracted morphine-induced increments in the threshold. These results suggest that the opiate system may be indirectly involved in certain aspects of the operant escape behavior induced by the DCG-stimulation.
著者
-
Gomita Yutaka
Department Of Hospital Pharmacy
-
Ichimaru Yasuyuki
Pharmaceutical Research Center Meiji Seika Kaisha Ltd
-
Araki Yasunori
Department Of Control Engineering Faculty Of Engineering Science Osaka University
-
Moriyama Minehiro
Department Of Pharmacology Daiichi College Of Pharmaceutical Sciences:(present Address)department Of
-
Ichimaru Yasuyuki
Pharmacology Department, Meiji Seika Pharmaceutical Science Research Center
関連論文
- Nicotinic Acetylcholine α4β2 Receptor Regulates the Motivational Effect of Intracranial Self Stimulation Behavior in the Runway Method
- Effect of Methamphetamine and Imipramine on Cerebral Ischemia-Induced Hyperactivity in Mongolian Gerbils
- ESTABLISHMENT OF NEUROTRANSMITTER-HYPERSENSITIVE PC12 VARIANT CELLS DEFICIENT IN NERVE GROWTH FACTOR-INDUCED NEURITE OUTGROWTH
- Immunosuppressant FK506 Induces Sustained Activation of MAP Kinase and Promotes Neurite Outgrowth in PC12 Mutant Cells Incapable of Differentiating
- Counseling of Patients with Bronchial Asthma, and Clinical Pharmacy Practice and Education of Pharmacy School Students
- Development and Application of a Cocaine-Selective Electrode (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
- Effect of Diazepam on the Runway Method Using Priming Stimulation of Intracranial Self Stimulation Behavior
- The 5-HT_ Receptor Full Agonist, 8-OH-DPAT Inhibits ACTH-Induced 5-HT_ Receptor Hyperfunction in Rats : Involvement of 5-HT_ Receptors in the DOI-Induced Wet-Dog Shakes in ACTH-Treated Rats(Pharmacology)
- Increased DOI-Induced Wet-Dog Shakes in Adrenocorticotropic Hormone-Treated Rats Are Not Affected by Chronic Imipramine Treatment : Possible Involvement of Enhanced 5-HT_-Receptor Expression in the Frontal Cortex
- Influence of Lactation on Plasma Phenobarbital Concentrations in Rats
- Pharmacokinetics of slow-release preparations of sodium valproate
- Simple and rapid analysis of lamotrigine, a novel antiepileptic, in human serum by high-performance liquid chromatography using a solid-phase extraction technique
- Pharmacokinetics of slow-release preparations of sodium valproate
- Neuronal Nicoticic Receptor and Psychiatric Disorders: Functional and Behavioral Effects of Nicotine
- Motivational Effect of Nomifensine in the Intracranial Self-Stimulation Behavior Using a Runway Method(Pharmacology)
- Selegilin Exerts Antidepressant-Like Effects During the Forced Swim Test in Adrenocorticotropic Hormone-Treated Rats
- Motivational Effects of Methamphetamine as Measured by the Runway Method Using Priming Stimulation of Intracranial Self-stimulation Behavior(Analytical Biochemistry)
- Effects of Imipramine and Bupropion on the Duration of Immobility of ACTH-Treated Rats in the Forced Swim Test : Involvement of the Expression of 5-HT_ Receptor mRNA(Pharmacology)
- Modulation of 8-OH-DPAT-Induced Hypothermia by Imipramine in Rats
- Effects of Long-Term Treatment With Calcium Antagonists on Periarterial Nerve Function in the Mesenteric Artery of Spontaneously Hyupertensive Rats
- Long-Term Treatment With Angiotensin Converting Enzyme Inhibitor Restores Reduced Calcitonin Gene-Related Peptide-Containing Vasodilator Nerve Function in Mesenteric Artery of Spontaneously Hypertensive Rats
- CHANGES IN CIRCADIAN RHYTHM OF LOCOMOTOR ACTIVITY INDUCED BY CEREBRAL ISCHEMIA IN MONGOLIAN GERBILS
- EFFECTS OF CLOBAZAM ON AMYGDALOID AND HIPPOCAMPAL KINDLED SEIZURES IN RATS
- Effects of Chronic Administration of Sibutramine on Body Weight, Food Intake and Motor Activity in Neonatally Monosodium Glutamate-Treated Obese Female Rats: Relationship of Antiobesity Effect with Monoamines
- Effect of Dopaminergic Drugs on the Reserpine-Induced Lowering of Hippocampal Theta Wave Frequency in Rats
- Examination of Particulate Contamination after Opening Ampoules : Relationship between Ampoule Inner-diameter and Glass Particle Accumulation after Opening Ampoules
- Potentiation of _L-Dopa-Induced Behavioral Excitement by Histamine H_1-Receptor Antagonists in Mice
- EFFECTS OF LIMBIC LESIONS, ESPECIALLY OF OLFACTORY BULBECTOMY ON SIMPLE CONDITIONED AVOIDANCE RESPONSE IN RATS
- Neither the 5-HT_ - nor the 5-HT_2 - Receptor Subtype Mediates the Effect of Fluvoxamine, a Selective Serotonin Reuptake Inhibitor, on Forced - Swimming - Induced Immobility in Mice
- 5-HT_ - Receptor Subtype Mediates the Effect of Fluvoxamine, a Selective Serotonin Reuptake Inhibitor, on Marble - Burying Behavior in Mice
- EFFECTS OF BENZODIAZEPINES ON LOW RATE RESPONDING FOR LOW CURRENT BRAIN STIMULATION REWARDS
- THE EMOTIONAL COMMUNICATION BASED ON METHAMPHETAMINE MORTALITY AS THE INDEX IN OLFACTORY BULBECTOMIZED MICE
- INFLUENCE OF AGGREGATION ON THE ACTION OF METHAMPHETAMINE IN LOCOMOTOR ACTIVITY
- Uniformity of Magnetic Properties in Amorphous Thin Films
- CHANGES IN SENSITIVITY TO CONVULSION IN MICE WITH OLFACTORY BULB ABLATION
- Differential Effects of Morphine on Operant Escape Behavior and Averse Symptom Induced by Dorsal Central Gray Stimulation in Rats
- Involvement of Dopaminergic Receptor Signaling in the Effects of Glutamatergic Receptor Antagonists on Conditioned Place Aversion Induced by Naloxone in Single-Dose Morphine-Treated Rats
- Effects of Neonatal Injections of Estrogen in Combination with Vitamin A on the Vaginal Epithelium of Adult Mice
- Effects of cholinergic drugs on aversive operant behavior induced by dorsal central gray stimulation in rats.
- Behavioral effects of HR-592, a new derivative of indole.
- Auto-titration technique using intracranial self-stimulation and effects of antianxiety drugs.
- Neural systems activated by the aversive stimulation of dorsal central gray.
- Effects of methamphetamine on regional cerebral glucose utilization in rats with unilateral lesion of substantia nigra.
- Influence of electric foot shock on pharmacokinetics of isosorbide dinitrate subcutaneously administered to rats.
- Influence of electric foot shock on pharmacokinetics of isosorbide dinitrate orally administered to rats.