Role of 5-Hydroxytryptamine2C Receptors in Marble-Burying Behavior in Mice
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概要
- 論文の詳細を見る
We examined the role of 5-hydroxytryptamine2C (5-HT2C) receptors in marble-burying behavior in mice. When administered alone, the selective 5-HT2C agonist WAY161503 (3 mg/kg) inhibited marble-burying behavior. Moreover, the selective 5-HT2C antagonist SB242084 (3 mg/kg) reversed the inhibition of marble-burying behavior by 2,5-dimethoxy-4-iodoamphetamine (DOI) (1 mg/kg) or WAY161503 (3 mg/kg). Similarly, SB242084 (1 mg/kg) reversed the inhibition of marble-burying behavior by fluvoxamine (30 mg/kg) or paroxetine (3 mg/kg). These results suggest that 5-HT2C receptors play a role in marble-burying behavior in mice.
著者
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IWASAKI Katsunori
Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University
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OKUNO Ryoko
Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University
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Oishi Ryozo
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University
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Egashira Nobuaki
Department Of Neuropharmacology Faculty Of Pharmaceutical Sciences Fukuoka University
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Iwasaki Katsunori
Department Of Mathematical Sciences The University Of Tokyo
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Okuno Ryoko
Department Of Neuropharmacology Faculty Of Pharmaceutical Sciences Fukuoka University
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Mishima Kenichi
Department Of Chemical Engineering Faculty Of Engineering Fukuoka University
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Fujiwara Michihiro
Department Of Neuroparmacology Faculty Of Pharmaceutical Sciences Fukuoka University
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Shirakawa Atsunori
Department Of Neuropharmacology Faculty Of Pharmaceutical Sciences Fukuoka University
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Nagao Masaki
Department of Neuropharmacology, Faculty of Pharmaceutical Science, Fukuoka University
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Nagao Masaki
Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University
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Nagao Masaki
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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