Benzylpiperazine Derivatives. VII. Studies on the Role of the Nitrogen Atom in the Cerebral Vasodilating Activity of 1-Benzyl-4-diphenyl-methylpiperazine Derivatives(Medicinal Chemistry,Chemical)
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概要
- 論文の詳細を見る
1-Benzyl-4-diphenylmethylpiperidine derivatives were prepared to investigate the role of the nitrogen atom in their cerebral vasodilating activity. The pharmacological test results revealed that the piperidine derivatives are roughly equipotent to the piperazine derivatives in our test system. Structure-activity analyses are presented.
- 公益社団法人日本薬学会の論文
- 1987-11-25
著者
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大高 博
Pharmaceuticals Research Center, Kanebo Ltd.,
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大高 博
New Drug Research Laboratories Kanebo Ltd.
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伊藤 敬三
鐘紡
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伊藤 敬三
Pharmaceuticals Research Center Kanebo Ltd.
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塚本 悟郎
Pharmaceuticals Research Center, Kanebo Ltd.
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塚本 悟郎
New Drug Research Laboratories Kanebo Ltd.
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金沢 稔郎
Pharmaceuticals Research Center, Kanebo Ltd.
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伊藤 敬三
Pharmaceutical Research Center Kanebo Co. Ltd.
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金沢 稔郎
Pharmaceuticals Research Center Kanebo Ltd.
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塚本 悟郎
Pharmaceutical Research Laboratory, Tanabe Seiyaku Co., Ltd.
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