Organic Phosphorus Compounds. IV : Asymmetric 4-(Benzothiazol-2-yl)benxylphosphonates as Potent Calcium Antagonistic Vasodilators
スポンサーリンク
概要
- 論文の詳細を見る
Various asymmetric or cyclic ester derivatives of the phosphonic acid moiety in the calcium antagonist fostedil (KB-944) were synthesized. The coronary vasodilator activity of these compounds was assessed by Langendorff's method. Among them, the ethyl isopropyl ester 12 showed the most potent activity, which was comparable to that of fostedil.
- 公益社団法人日本薬学会の論文
- 1990-03-25
著者
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塚本 悟郎
Pharmaceuticals Research Center, Kanebo Ltd.
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吉野 公一郎
Pharmaceuticals Research Center Kanebo Ltd.
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塚本 悟郎
New Drug Research Laboratories Kanebo Ltd.
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後藤 勝美
Pharmaceuticals Research Center, Kanebo Ltd.,
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高野 敏彦
Pharmaceuticals Research Center, Kanebo Ltd.,
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森田 富範
Pharmaceuticals Research Center, Kanebo Ltd.,
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森田 富範
Pharmaceuticals Research Center Kanebo Ltd.
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後藤 勝美
Pharmaceuticals Research Center Kanebo Ltd.
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高野 敏彦
Pharmaceuticals Research Center Kanebo Ltd.
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塚本 悟郎
Pharmaceutical Research Laboratory, Tanabe Seiyaku Co., Ltd.
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