Synthesis of 3-Glucuronides of Unconjugated and Conjugated Bile Acids
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概要
- 論文の詳細を見る
The 3-glucuronides of unconjugated, glyco- and tauro-conjugated bile acids have been prepared by an unequivocal route. Among three synthetic routes leading to the desired compounds, a method involving glucuronidation of the p-nitrophenyl ester by means of the Koenigs-Knorr reaction and subsequent conversion of the activated ester into the glyco-and tauro-conjugates was found to be most suitable. The nuclear magnetic resonance spectral data for bile acid glucuronides and related compounds are tabulated.
- 公益社団法人日本薬学会の論文
- 1980-04-25
著者
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砂崎 和彦
Pharmaceutical Institute, Tohoku University
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南原 利夫
Pharmaceutical Institute Tohoku University
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砂崎 和彦
Pharmaceutical Institute Tohoku University
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