Studies on Steroid Conjugates. IV. Synthesis of Catechol Estrogen Monoglucuronides
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概要
- 論文の詳細を見る
2-Hydroxyestradiol 2- and 3-monoglucuronides (X, V) were prepared from the suitably protected catechol estrogen derivatives employing Koenigs-Knorr reaction as shown in Chart 1. These synthetic glucuronides underwent readily hydrolysis to furnish 2-hydroxyestradiol and free glucuronic acid when incubated with beef-liver β-glucuronidase preparation.
- 公益社団法人日本薬学会の論文
- 1970-06-25
著者
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南原 利夫
Pharmaceutical Institute, Tohoku University
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本間 誠次郎
Pharmaceutical Institute Tohoku University
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南原 利夫
Pharmaceutical Institute Tohoku University
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