Studies on Steroid Conjugates. III. New Syntheses of 2-Methoxyestrogens
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概要
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The new synthetic routes leading to the 2-methoxyestrogens from the readily available compounds have been investigated. Utilization of both Friedel-Crafts and Baeyer-Villiger reactions with estrone and estradiol 3-methyl ethers gave the desired 2-methoxyestrogens in overall yield of ca. 50%. Fries rearrangement with estrone acetate and Friedel-Crafts reaction with 2-methoxy-3-deoxyestrogens were also undertaken. The chemical shifts of the aromatic protons of the 2,3-substituted estratrienes are collected in Table I and II.
- 公益社団法人日本薬学会の論文
- 1970-03-25
著者
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南原 利夫
Pharmaceutical Institute, Tohoku University
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本間 誠次郎
Pharmaceutical Institute Tohoku University
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秋山 節子
Pharmaceutical Institute, Tohoku University
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南原 利夫
Pharmaceutical Institute Tohoku University
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