The Bromination of 13α-Androstan-15-one
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概要
- 論文の詳細を見る
In order to examine the behaviors toward bromination 3β-acetoxy-5α, 13α-androstan-15-one (X) was prepared from the 17-keto steroid (I) according to the method worked out by Djerassi, et al. with the C/D-trans steroid (see Chart 1). On treatment with bromine in acetic acid in the presence of hydrogen bromide, bromination occurred exclusively at C-16 yielding a mixture of 16β-bromo and 16,16-dibromo derivatives (XI and XII), which could be separated readily by preparative thin-layer chromatography.
- 公益社団法人日本薬学会の論文
- 1971-12-25
著者
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南原 利夫
Pharmaceutical Institute, Tohoku University
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細野 宏
Pharmaceutical Institute Tohoku University
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碓氷 昌宏
Pharmaceutical Institute, Tohoku University
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呉 励然
Pharmaceutical Institute, Tohoku University
-
南原 利夫
Pharmaceutical Institute Tohoku University
-
碓氷 昌宏
Pharmaceutical Institute Tohoku University
-
呉 励然
Pharmaceutical Institute Tohoku University
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