New Derivatization for Liquid Chromatographic Resolution of Amino Acid Enantiomers

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概要

• 論文の詳細を見る

• A new method for liquid chromatographic resolution of amino acid enantiomers by the formation of diastereomers has been developed. A chiral reagent used for this purpose, (-)-α-methoxy-α-methyl-1-naphthaleneacetic acid (IIb), was readily prepared by fractionally crystallizing the (+)-α-methylbenzylamine salt. The diastereomers formed from amino acid methyl esters and IIb by the N, N'-dicyclohexylcarbodiimide method were efficiently resolved on the normal phase column.

• 社団法人日本薬学会の論文
• 1977-04-25

著者

• 南原 利夫

  Pharmaceutical Institute, Tohoku University

• 島田 和武

  東北大学薬学部

• 島田 和武

  Pharmaceutical Institute, Tohoku University

• 後藤 順一

  Pharmaceutical Institute Tohoku University

• 長谷川 正年

  Pharmaceutical Institute Tohoku University

• 中村 節子

  Pharmaceutical Institute Tohoku University

• 島田 和武

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 南原 利夫

  Pharmaceutical Institute Tohoku University

• 島田 和武

  Faculty Of Pharmaceutical Sciences Kanazawa University

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