THE BRIDGE LENGTH EFFECT ON SENSITIVITY IN STEROID ENZYME IMMUNOASSAY

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概要

• 論文の詳細を見る

• The effect of the bridge heterologous combination between antiserum and enzyme-labeled antigen on sensitivity in 11-deoxycortisol enzyme immunoassay has been investigated. The sensitivity of an assay system using a β-galactosidase-labeled antigen prepared from an 11-deoxycortisol derivative having a carboxymethylthio moiety as a bridge at C-4 was compared with one with an N-(carboxymethyl) carbamoylmethylthio moiety at C-4. The former assay proved to be more sensitive than the latter. This indicates that the bridge length is an important factor influencing the sensitivity of hapten enzyme immunoassay.

• 社団法人日本薬学会の論文
• 1985-02-25

著者

• 南原 利夫

  Pharmaceutical Institute, Tohoku University

• 細田 宏

  Pharmaceutical Institute Tohoku University

• 小林 典裕

  Pharmaceutical Institute Tohoku University

• 石井 肖

  Pharmaceutical Institute, Tohoku University

• 南原 利夫

  東北大学医学部薬学科

• 南原 利夫

  Pharmaceutical Institute Tohoku University

• 石井 肖

  Pharmaceutical Institute Tohoku University

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