THE EFFECT OF ALBUMIN ON THE UPTAKE OF BROMOSULFOPHTHALEIN BY ISOLATED RAT HEPATOCYTES
スポンサーリンク
概要
- 論文の詳細を見る
The initial rate of uptake of bromosulfophthalein (BSP) by isolated rat hepatocytes analyzed as a function of the unbound concentration of BSP was greater in the presence of albumin than in its absence, though the presence of albumin in the medium apparently decreased the uptake of BSP by hepatocytes analyzed as a function of the total concentration of BSP. This suggests that the uptake of BSP by isolated rat hepatocytes in the presence of albumin is not only dependent on the unbound concentration of BSP, but also is driven by the bound fraction of BSP.
- 公益社団法人日本薬学会の論文
著者
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AWAZU Shoji
Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Science
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MIZUMA Takashi
Department of Biopharmaceutics, Tokyo College of Pharmacy
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HORIE Toshiharu
Departments of Biopharmaceutice, Graduate School of Pharmaceutical Sciences, Chiba University
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AWAZU Shoji
東京薬科大学薬学部 薬物動態制御学教室
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Mizuma Takashi
Department Of Biopharmaceutics Tokyo College Of Pharmacy
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Mizuma Takashi
Department Of Biopharmaceutics And Drug Rational Research Center School Of Pharmacy Tokyo University
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Awazu Shoji
Deparment Of Biopharmaceutics Tokyo College Of Pharmacy
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Awazu S
Department Of Biopharmaceutics Tokyo College Of Pharmacy:department Of Pharmaceutics Research Center
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澤山 茂
東京農大 栄養
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Horie Toshiharu
Department Of Biopharmaceutics Graduate School Of Pharmaceutical Sciences Chiba University
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Awazu S
Department Of Biopharmaceutics School Of Pharmacy Tokyo University Of Pharmacy And Life Science
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Awazu S
Department Of Biopharmaceutics Tokyo College Of Pharmacy
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Mizuma Takashi
Department of Applied Chemistry, Faculty of Engineering, Osaka University
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