Kinetic Impact of presystemic Intestinal Metabolism on Drug Absorption:Experiment and Date Analysis for the Prediction of In Vivo Absorption from In Vitro Data
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概要
- 論文の詳細を見る
- 2003-02-20
著者
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MIZUMA Takashi
Department of Biopharmaceutics, Tokyo College of Pharmacy
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Mizuma Takashi
Department Of Biopharmaceutics School Of Pharmacy Tokyo University Of Pharmacy And Life Science
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Mizuma Takashi
Department Of Biopharmaceutics And Drug Rational Research Center School Of Pharmacy Tokyo University
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Mizuma Takashi
Department of Applied Chemistry, Faculty of Engineering, Osaka University
関連論文
- IMPROVEMENT OF POORLY ABSORBABLE DRUG BY INTESTINAL GLUCOSE TRANSPORT SYSTEM
- HETEROGENEOUS DISTRIBUTION OF THE CONJUGATION ACTIVITY OF ACETAMINOPHEN AND p-NITROPHENOL IN ISOLATED RAT LIVER CELLS
- MULTIPLE FORMS OF ARYL SULFOTRANSFERASE FOR ACETAMINOPHEN SULFATE CONJUGATION IN RAT LIVER CYTOSOL
- HETEROGENEOUS DISTRIBUTION OF CONJUGATION ACTIVITIES OF HARMOL IN ISOLATED RAT LIVER CELLS
- Transport and Recognition of Aminopeptidase-Resistant Cellobiose-Coupled Tyrosylglycylglycine by Intestinal Na^+/Glucose Cotransporter (SGLT1) : Recognition of Suger Conjugates by SGLT1 Is Much Less Restricted than Transport
- Kinetic Impact of presystemic Intestinal Metabolism on Drug Absorption:Experiment and Date Analysis for the Prediction of In Vivo Absorption from In Vitro Data
- Preference of Peyer's Patches to Jejunal Epithelium for Intestinal Absorption of Oligopeptides, Tyrosylglycylglycine and D-Kyotorphin
- ACTION MECHANISM OF PERMEATION ENHANCERS IN PARACELLULAR PATHWAY
- Photo-Stability of Drugs in Enteral Hyperalimentation Solutions and Its Influence on the Dose Given by a Continuous Infusion
- INTESTINAL ABSORPTION OF MACROMOLECULAR COMPOUNDS-IS ITS IMPROVEMENT POSSIBLE?
- Evaluation of Dose of Unstable Drug Administered by Infusion
- ARYL SULFOTRANSFERASE IN RAT LIVER : MULTIPLICITY AND SUBSTRATE SPECIFICITY
- ALBUMIN-MEDIATED UPTAKE MECHANISM OF DRUG BY ISOLATED HEPATOCYTES
- CHARACTERIZATION OF THE INTERACTION OF ALBUMIN WITH ISOLATED RAT LIVER CELLS TO REVEAL THE MECHANISM OF ALBUMIN-MEDIATED HEPATIC TRANSPORT
- THE EFFECT OF ALBUMIN ON THE UPTAKE OF BROMOSULFOPHTHALEIN BY ISOLATED RAT HEPATOCYTES
- p-NITROPHENOL SULFATION IN RAT LIVER CYTOSOL : MULTIPLE FORMS AND SUBSTRATE INHIBITION OF ARYL SULFOTRANSFERASE
- Critical Factor in Intestinal Absorption of Peptide Drugs : Quantitative Analysis of Peptide Drug Absorption which is Competitive Process of Metabolism and Transport
- High-performance liquid chromatographic determination and identification of acyl migration and photodegradation products of furosemide 1-O-acyl glucuronide
- IRREVERSIBLE BINDING OF FUROSEMIDE TO HUMAN SERUM ALBUMIN BY METABOLIC ACTIVATION, PHOTOACTIVATION AND BOTH ACTIVATIONS
- Concentration-Dependent Atypical Intestinal Absorption of Cyclic Phenylalanylserine: Small Intestine Acts as an Interface between the Body and Ingested Compounds(Biopharmacy)
- Factors Affecting Glucuronidation Activity in Caco-2 Cells
- Molecular structures of (2)(2,5)(7,7,8,8-tetracyanoquinodimethano)(2)paracyclophane and 14,17-dimethoxy(2)(2,5)(7,7,8,8-tetracyanoquinodimethano)(2)paracyclophane.
- The crystal structure of 2,11,20-trithia(3.3.3)(1,2,4)(1,3,5)cyclophane and molecular structures of unsymmertically tris-bridged (2.2.2)(1,2,4)(1,3,5) and (2.2.2)(1,2,4)(1,2,5)cyclophanes, estimated by molecular conformational analysis.
- Molecular structure of (2)(2,5)(7,7,8,8-tetracyanoquinodimethano)-(2)(1,4)naphtalenophane.