Antitumor Activity of 2-Acylamino-1,3,4-thiadiazoles and Related Compounds

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概要

• 論文の詳細を見る

• 2-Nitrosoureido-1,3,4-thiadiazoles were effective against both mouse lymphoid leukemia L1210 and rat ascites hepatoma AH13. Some 2-acylamino-1,3,4-thiadiazoles were also effective against L1210. The anti-L1210 action of these 2-acylamino-1,3,4-thiadiazoles was blocked by administration of nicotinamide. Among these compounds, 2-propanoylamino-1,3,4-thiadiazole was the most effective against L1210,with a maximum T/C% of 166.

• 公益社団法人日本薬学会の論文
• 1982-12-25

著者

• 宮原 誠

  National Institute of Hygienic Sciences, University of Tokyo

• 神谷 庄造

  National Institute of Hygienic Sciences, University of Tokyo

• 宮原 誠

  国立医薬品食品衛生研究所 食品部

• 丹野 雅幸

  National Institute of Hygienic Sciences

• 宮原 美知子

  国立医薬品食品衛生研究所 衛生微生物部

• 宮原 誠

  National Institute Of Hygienic Sciences

• 宮原 美知子

  National Institute of Hygienic Sciences

• 末吉 祥子

  National Institute of Hygienic Sciences

• 中舘 正弘

  National Institute of Hygienic Sciences

• 神谷 庄造

  National Institute Of Hygienic Sciences

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