Synthesis of 4-Azidoquinoline 1-Oxides and Related Compounds

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概要

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• 4-Azidoquinoline 1-oxides with methyl, cyano and carbamoyl groups at the 2 position, and chloro and trifluoromethyl groups at the 7 position were prepared. 4-Azidocinnoline 1-oxide and 2-oxide were also prepared. Their antitumor and mutagenic activities were tested in comparison with those of a carcinogenic, carcinostatic and mutagenic compound, 4-nitroquinoline 1-oxide.

• 公益社団法人日本薬学会の論文
• 1980-05-25

著者

• 中島 利章

  Central Research Laboratories, SS Pharmaceutical Co., Ltd.,

• 宮原 美知子

  国立医薬品食品衛生研究所 衛生微生物部

• 柳町 きみゑ

  National Institute of Hygienic Sciences

• 中島 利章

  Central Research Laboratory Ss Pharmaceutical Co. Ltd.

• 神谷 庄造

  National Institute Of Hygienic Sciences

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