Chromatographic Separation of Armatic Guest Compounds by a Gel-Immobilized Water-Soluble Cyclophane
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概要
- 論文の詳細を見る
An agarose gel upon which a water-soluble cyclophane having three quaternary nitrogens was immobilized, Gel-QCP (3), was synthesized and its properties as a chromatographic stationary phase were studied. The affinity of Gel-QCP for several neutral and anionic aromatic guests was broadly consistent with that of the parent cyclophane (2). This suggests that the guest separation is attributable to the formation of inclusion complexes between the cyclophane moiety of Gel-QCP and the guests. Non-specific electrostatic interaction also influences anionic guests, but this effect is reduced by using an aqueous solution of NaCl as an eluent.
- 公益社団法人日本薬学会の論文
- 1992-03-25
著者
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古賀 憲司
Faculty of Pharmaceutical Sciences, University of Tokyo
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古賀 憲司
東京大学
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Koga Kenjiro
Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences Hokuriku University
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小田嶋 和徳
Faculty of Pharmaceutical Sciences, University of Tokyo
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真鍋 敬
Faculty of Pharmaceutical Sciences, University of Tokyo
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小田嶋 和徳
Graduate School Of Pharmaceutical Sciences The University Of Tokyo
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