ASYMMETRIC REDUCTION OF ARYLGLYOXYLIC ACIDS VIA・HOST-GUEST COMPLEX FORMATION WITH OPTICALLY ACTIVE PARACYCLOPHANES
スポンサーリンク
概要
- 論文の詳細を見る
Reduction of 1-naphthylglyoxylic acid (2c) by inclusion complex formation with optically active paracyclophane (1a) followed by treatment with sodium borohydride in acidic water gave, after esterification with diazomethane, (R)-1-naphthylglycolic acid methyl ester (4c) in 9.7% ee. A working hypothesis is proposed to describe the mechanism of this reaction.
- 社団法人日本薬学会の論文
- 1985-08-25
著者
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古賀 憲司
Faculty of Pharmaceutical Sciences, University of Tokyo
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Koga Kenjiro
Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences Hokuriku University
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小田嶋 和徳
Faculty of Pharmaceutical Sciences, University of Tokyo
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高橋 一朗
Faculty Of Pharmaceutical Sciences University Of Tokyo
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小田嶋 和徳
Graduate School Of Pharmaceutical Sciences The University Of Tokyo
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