Stereochemical Studies. XLVIII. Stereoselective Synthesis of 6-Deoxy-L-hexose Derivatives from L-Alanine without a Resolution Step
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概要
- 論文の詳細を見る
A new stereoselective synthesis of methyl α-L-amicetoside (11), methyl α-L-mycaminoside (14) and methyl α-L-oleandroside (17) starting from L-alanine is described. It is shown that methyl 2,3,6-trideoxy-α-L-hex-2-enopyranosid-4-ulose (8) is readily accessible from L-alanine in optically pure state and is a potential intermediate for the synthesis of various kinds of 6-deoxy-L-hexoses.
- 公益社団法人日本薬学会の論文
- 1977-10-25
著者
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溝口 富茂
Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.
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Koga Kenjiro
Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences Hokuriku University
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大関 正勝
Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.
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古賀 憲司
Pharmaceutical Sciences, University of Tokyo
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山田 俊一
Pharmaceutical Sciences, University of Tokyo
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溝口 富茂
Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.
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