MOLECULAR RECOGNITION AND DISCRIMINATION OF HYDROPHOBIC GUESTS IN WATER BY QUATERNARY AMMONIUM CYCLOPHANES HAVING DIARHLMETHANE UNITS

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概要

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• A series of quaternary ammonium cyclophanes, 2b〜e and 4a〜d, having well-defined hydrophobic cavities rationally designed with diphenylmethane and naphthylphenylmethane units, respectively, were synthesized and fully characterized. A systematic study on the molecular recognition and discrimination properties of these hosts in neutral water was carried out. Whereas host 2 having diphenylmethane units formed inclusion complexes selectively with aromatic guests, host 4 having naphthylphenylmethane units were proved to form inclusion complexes with bulky aliphatic guests that were not complexed by host 2.

• 社団法人日本薬学会の論文
• 1989-01-25

著者

• 古賀 憲司

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 川上 肇

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 三輪 篤史

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• Koga Kenjiro

  Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences Hokuriku University

• 小田嶋 和徳

  Faculty of Pharmaceutical Sciences, University of Tokyo

• SASAKI Isabelle

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 小田嶋 和徳

  Graduate School Of Pharmaceutical Sciences The University Of Tokyo

• Sasaki Isabelle

  Faculty Of Pharmaceutical Sciences University Of Tokyo

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