DESIGN, SYNTHESIS, AND PROPERTIES OF NOVEL WATER-SOLUBLE CYCLOPHANES HAVING NAPHTHYLPHENYLMETHANE UNITS AS HOSTS FOR ALIPHATIC AND AROMATIC GUESTS
スポンサーリンク
概要
- 論文の詳細を見る
Novel water-soluble cyclophanes (2a, 2b) which act as hosts having hydrophobic cavities were made by connecting two naphthylphenylmethane units and two tetramethylene bridges via four nitrogens. ^1H NMR spectral studies have shown that in water these cyclophanes form inclusion complexes with aliphatic as well as aromatic guests.
- 社団法人日本薬学会の論文
- 1985-12-25
著者
-
古賀 憲司
Faculty of Pharmaceutical Sciences, University of Tokyo
-
川上 肇
Faculty Of Pharmaceutical Sciences University Of Tokyo
-
Koga Kenjiro
Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences Hokuriku University
-
吉野 収
(present Address)national Institute Of Radiological Sciences
-
小田嶋 和徳
Faculty of Pharmaceutical Sciences, University of Tokyo
-
吉野 収
Faculty of Pharmaceutical Sciences, University of Tokyo
-
小田嶋 和徳
Graduate School Of Pharmaceutical Sciences The University Of Tokyo
関連論文
- Stereochemical Studies. XIII. Determination of the Absolute Configuration of Mercaptosuccinic Acid by Chemical Correlation with Glyceraldehyde
- Studies on Opically Active Amino Acids. VII. Stereoselective Synthesis of l-Norephedrine Hydrochloride from D-Phenylalanine
- Studies on Optically Active Amino Acids. V. Synthesis of Optically Active α-Aminoalcohols by the Reduction of α-Amino Acid Esters with Sodium Borohydride
- Studies on Optically Active Amino Acids. IV. A New Synthetic Approach to Chloramphenicol Base from L-Phenylalanine.
- NMRを用いて糖タンパク質分子中の糖鎖を原子レベルで見る
- Stereoselective Reactions. XVI. : Total Synthesis of (-)-β-Bourbonene by Employing Asymmetric (2+2) Photocycloaddition Reaction of Chiral Butenolide
- 21 不斉(2+2)光環化付加反応による抗腫瘍性ジテルペン、スパトールの不斉全合成へのアプローチ
- Stereoselective Reactions. II. Asymmetric Synthesis of β-Substituted Aldehydes by Michael Reaction using Chiral α, β-Unsaturated Aldimines
- Stereoselective Reactions. I. A highly Efficient Asymmetric Synthesis of β-Substituted Aldehydes via 1,4-Addition of Grignard Reagents to optically Active α, β-Unsaturated Aldimines
- Stereochemical Studies. LIV. A Biogenetic-type Asymmetric Synthesis of optically Active Galanthamine from L-Tyrosine
- MOLECULAR RECOGNITION AND DISCRIMINATION OF HYDROPHOBIC GUESTS IN WATER BY QUATERNARY AMMONIUM CYCLOPHANES HAVING DIARHLMETHANE UNITS
- DESIGN, SYNTHESIS, AND PROPERTIES OF NOVEL WATER-SOLUBLE CYCLOPHANES HAVING NAPHTHYLPHENYLMETHANE UNITS AS HOSTS FOR ALIPHATIC AND AROMATIC GUESTS
- ASYMMETRIC REDUCTION OF ARYLGLYOXYLIC ACIDS VIA・HOST-GUEST COMPLEX FORMATION WITH OPTICALLY ACTIVE PARACYCLOPHANES
- Stereoselective Reactions. III. A highly Efficient Method for the Asymmetric Synthesis of 2-Alkylcycloalkanones via Chiral Chelated Lithioenamines
- Stereoselective Reactions. XXII. Design and Synthesis of Chiral Chelated Lithium Amides for Enantioselective Reactions
- REINVESTIGATION ON THE OPTICAL PURITIES OF OPTICALLY ACTIVE TRIMETHYLSILYL ENOL ETHERS OF 4-SUBSTITUTED CYCLOHEXANONES
- Biomimetic Studies Using Artificial Systems. VI. Design and Synthesis of Novel Cyclophanes Having Eight Carboxyl Groups on the Aromatic Rings
- A NOVEL WATER-SOLUBLE CYCLOPHANE AS A HOST FOR CATIONIC, ANIONIC, AND NEUTRAL AROMATIC GUESTS
- モレキュラ-・クレフトとキラル識別--Rebek教授の研究から (モレキュラ-・キラリティ---高次機能分子の開拓と創薬への展開をめざして) -- (キラル識別のメカニズムを追う)
- Chromatographic Separation of Armatic Guest Compounds by a Gel-Immobilized Water-Soluble Cyclophane
- Stereoselective Reactions. XIX. Asymmetric Dihydroxylation of Olefins by Employing Osmium Tetroxide-Chiral Amine Complexes
- 68 不斉酸化反応を用いるアントラサイクリン系抗生物質の短段階不斉合成(口頭発表の部)
- 4酸化オスミウムを用いたオレフィンの不斉酸化反応 (1987年の化学-6-)
- ENANTIOSELECTIVE DARZENS REACTION : ASYMMETRIC SYNTHESIS OF trans-GLYCIDIC ESTERS MEDIATED BY CHIRAL LITHIUM AMIDES
- Amino Acids and Peptides. II. A One-Step Synthesis of Atropine and Other Related Alkaloids from dl-Phenylalanine 3α-Tropanyl Ester
- 8 PhenylalanineからTropic acidへの非酵素的転換反応
- Stereochemical Studies. XVII. Nitrous Acid Deaminations of (R)-α-Methylphenylalanine and Its Methyl Ester in Acetic Acid
- Stereoselective Reactions. XX. Synthetic Studies on Optically Active β-Lactams. III. Stereocontrolled Synthesis of Chiral Intermediate to (+)-Thienamycin from D-Glucose
- Clove Oil Prevents Glycyrrhizin Gel Formation in Aqueous Solution
- Preparation and Rectal Absorption of Highly Concentrated Glycyrrhizin Solution(Biopharmacy)
- A Simple Method for the Selection of a Suitable Emulsifier Based on Color Difference
- Effects of Fatty Acid Glycerol Esters on Intestinal Absorptive and Secretory Transport of Ceftibuten
- Modification of Ceftibuten Transport by Changes in Lipid Fluidity Caused by Fatty Acid Glycerol Esters
- Effects of Fatty Acid Sucrose Esters on Ceftibuten Transport by Rat Intestinal Brush-Border Membrane Vesicles
- Contribution of Hydrophobicity of Nonionic Detergents to Membrane Lipid Fluidity and Disopyramide Uptake by Rat Intestinal Brush-Border Membrane Vesicles
- Stereoselective Reactions. XVIII. : Synthesis and Cytotoxicity of the Demethyl Derivatives of Steganes
- ナフタレン環への共役付加反応--不斉反応への展開 (1990年の化学-8-)
- ASYMMETRIC α-ALKYLATION OF CYCLOHEXANONE BY MEDIATION OF A CHIRAL LIGAND AND THE LEAVING-GROUP EFFECT OF ELECTROPHILES ON ENANTIOSELECTIVITY
- 新しい制がん剤の合成 (1989年の化学-8-)
- Stereoselective Reactions.XXXIV.^
- Stereoselective Reactions.XXXIII^. Design and Synthesis of Chiral Bidentate Amines Having a Bulky Group on the Chiral Carbon
- キラル塩基を用いる不斉合成
- Stereoselective Reactions. XXVII. Solution Structures of a Chiral Tridentate Lithium Amide in Relation to Enantioselective Deprotonation of 4-tert-Butylcyclohexanone
- ENANTIOSELECTIVE HORNER-WADSWORTH-EMMONS REACTION USING CHIRAL LITHIUM 2-AMINOALKOXIDES
- Approaches to Catalytic Asymmetric Formation and Reactions of Lithium Enolates
- Biomimetic Studies Using Astificial Systems. V. : Design and Synthesis of Novel Water-Soluble Bis-cyclophanes
- Stereoselective Reactions. XI. : Asymmetric Alkylation of Cyclohexanone via Chiral Chelated Lithioenamines Derived from D-Camphor Derivatives
- 膜電位の変化を生起するホストゲスト分子認識 (1995年の化学-2-)
- 有機化学におけるホスト・ゲスト現象 (ホスト・ゲストの化学--その多分野へのひろがり)
- シロクファン純人工ホスト化合物としての利用 (1981年の化学-5-)
- SYNTHETIC STUDIES TOWARD TRICHOTHECENE SESQUITERPENES. SYNTHESIS OF AN OPTICALLY PURE KEY INTERMEDIATE FOR CALONECTRIN USING HIGHLY STEREOSELECTIVE CYCLIZATION(Communications to the Editor)
- リチウムエノラートの触媒的不斉反応 (特集 ナノ・ケモテクノロジーへの招待--奈良先端科学技術大学院大学物質創成科学研究科)
- キラルなリチウムアミドを用いる不斉脱プロトン化反応 (1986年の化学-8-)
- 1 α-アミノ酸から光学活性Carene骨格の合成研究 : (+)-Car-2-eneの合成
- 不斉塩基を用いる不斉プロトン化反応 (1993年の化学-7-)
- NOVEL BICYCLIC CHIRAL CROWN ETHERS HAVING A p-XYLENEDIOXY UNIT WITH INPROVED COMPLEX STABILITY AND RATE-ENHANCEMENT IN THE INTRA-COMPLEX THIOLYSIS OF α-AMINO ACID ESTER SALTS
- キラル塩基を用いる不斉アルキル化反応 (1991年の化学-7-)
- Stereoselective Reactions. V. Design of the Asymmetric Synthesis of Lignan Lactones. Synthesis of optically Active Podorhizon and Deoxypodorhizon by 1,3-Asymmetric Induction
- Biomimetic Studies Using Artificial Systems. II. Enantioselective Thiolysis of D- or L-α-Amino Acid Ester Salts by Thiol-Bearing Chiral Crown Ethers as an Enzyme Model
- Studies on Optically Active Amino Acids.XIII.Racemization of N-Benzoylanilides of Optically Active Proline and Pipecolic Acid
- Studies on Optically Active Amino Acids. XII.Synthesis, Resolution and Racemization of Bicyclic α-Amino-ketones
- Stereoselective Reactions. IX. Synthetic Studies on Optically Active β-Lactams. I. Chiral Synthesis of Carbapenam and Carbapenem Ring Systems Starting from (S)-Aspartic Acid
- SYNTHETIC STUDIES ON OPTICALLY ACTIVE β-LACTAMS. STEREOCONTROLLED SYNTHESIS OF CHIRAL THIENAMYCIN INTERMEDIATE FROM D-GLUCOSE
- Stereoselective Reactions. XII. : Synthesis of Antitumor-Active Steganacin Analogs, Picrosteganol and Epipicrosteganol, by Selective Isomerization
- 30 光学活性アンスラサイクリノンの不斉合成
- Asymmetric Halolactonization Reactions. 3. Asymmetric Synthesis of optically Active Anthracyclinones
- Synthesis of Enantiomeric Pairs of Vicinal-Diols from L-α-Amino Acids by the Use of Organolithium Reagents : Its Application to optically Active Epoxyterpene Synthesis
- Synthesis of optically Active α-Alkyl or α-Aryl Acids from L-α-Amino Acids by the Use of Organocopper Reagents
- Functionalized Macrocycles. I. Synthesis of Thiol-bearing Crown Ethers as an Approach to Regioselective Catalysts
- 49 光学活性α-アミノ酸を用いる各種天然糖の合成 : 五炭糖及び六炭糖の立体特異的合成
- Stereochemical Studies. XLVIII. Stereoselective Synthesis of 6-Deoxy-L-hexose Derivatives from L-Alanine without a Resolution Step
- Chemistry of Amino Acids. III. Reduction of Phenylalanine Ethyl Ester and Its Derivatives with Sodium Borohydride.
- Stereochemical Studies. XII. Effects of Neighboring Functional Groups on 1,2-Asymmetric Induction in the Reduction of Propiophenone Derivatives by Catalytic Hydrogenation
- Stereochemical Studies. XXXI. Total Synthesis of Several D-Pentose Derivatives. Stereochemical Courses of the Synthesis of Four Methyl 2,3-Anhydro-5-O-benzyl-D-pentofuranosides from L-Glutamic Acid and Their Reactions with Nucleophiles
- Stereochemical Studies. XVI. Deaminative Acetolyses of L-Valine and L-Valine Benzyl Ester
- Biomimetic Studies Using Artificial Systems. IV. : Biomimetic Peptide Synthesis by Using Multi-Functionalized Crown Ethers as a Novel Enzyme Model. A New Concept in Mimicking of Enzyme-Catalyzed Bond-Forming Reactions
- クラウン化合物によるイオン認識 (分子の認識と機能の発現)
- Amino Acids and Peptides. III. A New Synthetic Approach to N-Acylated α-Amino Aldehydes from N-Acylated α-Amino Acids by Catalytic Reduction of Their Mixed Carbonic-Carboxylic Acid Anhydrides with Palladium-Charcoal
- Stereochemical Studies. XV. Neighboring Aryl Group Participation in Nitrous Acid Deaminations of L-Phenylalanine and Its p-Nitro and p-Methoxy Derivatives. Conversion of L-Phenylalanine to naturally Occurring S-Tropic Acid
- Stereochemical Studies. XIV. Studies on the Neighboring Aryl Group Participation in Nitrous Acid Deaminations of L-Phenylalanine Ethyl Ester and Its p-Nitro and p-Methoxy Derivatives
- Stereochemical Studies. LII. Studies on the Stereochemical Courese in Deaminative Bromination of 3,5-Dichloro-L-tyrosine and in Amination of the Corresponding α-Bromo Acid. Existence of Strong Neighboring "Phenoxide"Group Participation
- キレ-ト構造を有するキラルリチウムジアルキルアミドの会合状態と反応性 (1992年の化学-7-)
- Allylic strain conceptと立体選択的反応のデザイン--キレ-ト形成によらないコンホメ-ションの固定
- エステルエノレ-トの新しい立体選択的アルキル化反応 (1985年の化学-8-)
- Chemistry of Sodium Borohydride and Diborane. IV. Reduction of Carboxylic Acids to Alcohols with Sodium Borohydride through Mixed Carbonic-Carboxylic Acid Anhydrides
- Stereoselective Reactions. VIII. Stereochemical Requirement for the Benzylic Oxidation of Lignan Lactone. A Highly Selective Synthesis of the Antitumor Lignan Lactone Steganacin by the Oxidation of Stegane
- Stereoselective Reactions. VII. Synthesis of Racemic and Optically Pure Stegane, Isostegane, Picrostegane, and Isopicrostegane via Highly Selective Isomerization
- 42 光学活性ブチロラクトン誘導体をSynthonとして用いる合成研究 : 天然抗腫瘍性リグナン類の不斉合成
- Stereoselective Reactions. X. Total Synthesis of Optically Pure Antitumor Lignan, Burseran
- A Simple Method for the Selection of a Suitable Emulsifier Based on Color Difference
- Stereochemical Studies. LI. Stereochemical Courses of Deaminative Bromination of L-Aspartic Acid and Its Esters
- キラルなエナミンを用いる不斉Michael反応 (1988年の化学-8-)
- 42 抗腫瘍性セスキテルペン(+)-イバリンの不斉全合成
- 有機化学--ステガナシンの不斉的合成 (1980年の化学-6-)
- 高選択的不斉アルキル化反応 (高選択的反応--新しい有機合成) -- (不斉合成)
- Stereochemical Studies. L. Reductive Decyanization of α-Amino Nitriles with Sodium in Liquid Ammonia. An Alternate Method for the Application to the Asymmetric Synthesis of optically Active Natural Products
- Stereochemical Studies. XLIX. A Biogenetic-type Total Synthesis of Natural (+)-Maritidine from L-Tyrosine using highly Specific Asymmetric Cyclization
- Stereochemical Studies. XVIII. Nitrous Acid Deaminations of threo- and erythro-Phenylserine and Their Methyl Esters in Acetic Acid
- Stereochemical Studies. XI. Changes in the Stereochemical Course of 1,2-Asymmetric Induction in the Reduction of N-Substituted 2-Aminopropiophenone Derivatives with Sodium Borohydride
- Stereochemical Studies. X. Effects of Neighboring Functional Groups on 1,2-Asymmetric Induction in the Reduction of Propiophenone Derivatives with Sodium Borohydride