Amino Acids and Peptides. II. A One-Step Synthesis of Atropine and Other Related Alkaloids from dl-Phenylalanine 3α-Tropanyl Ester

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概要

• 論文の詳細を見る

• Atropine (VI), littorine (VII), apoatropine (IX), and related compounds have been synthesized by a one-step deamination reaction from dl-phenylalanine 3α-tropanyl ester (V). The amino ester (V) was obtained by coupling tropine with N-phthalyl-dl-phenylalanyl chloride (III) followed by hydrazinolysis with an equimolar amount of hydrazine hydrate.

• 公益社団法人日本薬学会の論文
• 1971-12-25

著者

• 山田 俊一

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 塩入 孝之

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 古賀 憲司

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 山田 俊一

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 竹内 義雄

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 塩入 孝之

  Faculty Of Pharmaceutical Sciences Nagoya City University

• Koga Kenjiro

  Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences Hokuriku University

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