Studies on Optical Rotatory Dispersion and Circular Dichroism.I.Absolute Configuration of Cyclic α-Amino-ketones and Octant Rule

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概要

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• The absolute configurations of cyclic amino-ketones, hexahydro-1(5H)-indolizinone (III), hexahydro-2H-quinolizin-1(6H)-one(IV), 3,4,11,11a-tetrahydro-2H-benzo [b] quinolizin-1(6H)-one (V) and 3,4,11,11a-tetrahydro-1H-benzo [b] quinolizin-2(6H)-one (XIX) were determined by the chemical correlation with indolizidine (IX), 1-methylenequinolizidine (X), 1,3,4,6,11,11a-hexahydro-2H-benzo [b] quinolizine (XII) and phenylalanine, respectively. A good agreement of the octant rule predictions with the experimental results was observed in the cases of hexahydro-1H-pyrrolizin-1-one (II), III and XIX, while the reverse rtesult to the predictions was obtained in IV and V.

• 公益社団法人日本薬学会の論文
• 1967-04-25

著者

• 山田 俊一

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 国枝 武久

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 山田 俊一

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 国枝 武久

  Faculty Of Pharmaceutical Sciences Kumamoto University

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