Stereochemical Studies. XXVI. Asymmetric Synthesis using Proline Derivatives of optically Active Various 4,4-Disubstituted 2-Cyclohexenones with Enamine Alkylation

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概要

• 論文の詳細を見る

• Enamines III, prepared from some disubstituted acetaldehydes I and L-proline pyrrolidide (II), were alkylated with methyl vinyl ketone to generally afford optically active 4,4-disubstituted 2-cyclohexenones V. This asymmetric synthesis is found to be widely applicable, their absolute configurations could be deduced by a comparison of the two substituents.

• 公益社団法人日本薬学会の論文
• 1973-10-25

著者

• 山田 俊一

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 山田 俊一

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 大谷 元治

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 大谷 元治

  Tokyo Research Laboratories Kowa Company Ltd.

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