Stereochemical Studies. XXXV. A Biogenetic-type Asymmetric Cyclization. Syntheses of optically Active α-Cyclocitral and trans-α-Damascone

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• Application of the biogenetic-type cyclization of citral (2) via its enamine, which was developed by us as described in the preceding paper, to the asymmetric synthesis, has been found to give (R) (+)-α-cyclocitral ((R) (+)-4) in at most 33% optical yield. (R) (+)-4 thus prepared was successfully converted to (R) (+)-trans-α-damascone ((R) (+)-6), a famous perfume which has fragrant odor, without racemization.

• 公益社団法人日本薬学会の論文
• 1975-02-25

著者

• 柴崎 正勝

  東大院薬

• 柴崎 正勝

  Faculty Of Pharmaceutical Sciences Teikyo University:(present Address)faculty Of Pharmacertical Scie

• 山田 俊一

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 山田 俊一

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• 寺島 孜郎

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 柴崎 正勝

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 寺島 孜郎

  (財)相模中央化学研究所

• 寺島 孜郎

  Faculty Of Pharmaceutical Sciences University Of Tokyo:(present Address)sagami Chemical Research Cen

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