Synthesis of dl-9 (O)-Methano-△^6-prostaglandin I_1
スポンサーリンク
概要
- 論文の詳細を見る
Biologically interesting 9 (O)-methano-△^6-prostaglandin I_1 (9 (O)-methano-△^6-PGI_1), a chemically stable analog of prostacyclin (PGI_2), was efficiently synthesized from 1,3-cyclooctadiene with high stereo- and regiochemical control. In all three biological test systems examined, 9 (O)-methano-△^6-PGI_1 was found to be considerably less active than prostaglandin E_1 (PGE_1).
- 公益社団法人日本薬学会の論文
- 1983-12-25
著者
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柴崎 正勝
Faculty Of Pharmaceutical Sciences Teikyo University:(present Address)faculty Of Pharmacertical Scie
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池上 四郎
Faculty of Pharmaceutical Sciences, Teikyo University
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柴崎 正勝
Faculty Of Pharmaceutical Sciences Hokkaido University
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伊関 克彦
Faculty of Pharmaceutical Sciences, Teikyo University
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間瀬 俊明
Sagami Chemical Research Center
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岡崎 徳二
Research Laboratories, Ohta Pharmaceutical Co., Ltd.,
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間瀬 俊明
Faculty of Pharmaceutical Sciences, Teikyo University
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岡崎 徳二
Faculty of Pharmaceutical Sciences, Teikyo University
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伊関 克彦
Faculty Of Pharmaceutical Sciences Teikyo University:(present Address)pharmaceuticals Laboratory Res
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池上 四郎
Faculty Of Pharmaceutical Sciences Teikyo University
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岡崎 徳二
Research Laboratories Ohta Pharmaceutical Co. Ltd.
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