SYNTHESIS OF CIS-BICYCLO[4.3.0]NON-2-ENE DERIVATIVES. : THE POTENT HOMOISOCARBACYCLIN ANALOGS

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概要

• 論文の詳細を見る

• Synthesis of homoisocarbacyclin has been achieved efficiently by a general strategy with stereo-and regiochemical control. One of homoisocarbacyclin derivatives, 3-oxa homoisocarba-cyclin analog <(4)>___〜, was shown to be potently active in inhibiting gastric ulcer. Another analog, conjugated diene derivative <(5)>___〜, was found to have a biological profile similar to prostacyclin.

• 社団法人日本薬学会の論文
• 1989-06-25

著者

• 柴崎 正勝

  Faculty Of Pharmaceutical Sciences Teikyo University:(present Address)faculty Of Pharmacertical Scie

• 青木 剛

  Fukushima Research Laboratories Toa Eiyo Ltd.

• 柴崎 正勝

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 成田 仙一

  Fukushima Research Laboratories, Toa Eiyo Ltd.,

• 高橋 敦男

  Fukushima Research Laboratories, TOA EIYO Ltd.,

• 佐藤 博泰

  Fukushima Research Laboratories, TOA EIYO Ltd.,

• 佐藤 博泰

  Fukushima Research Laboratories Toa Eiyo Ltd.

• 成田 仙一

  Fukushima Research Laboratories Toa Eiyo Ltd.

• 高橋 敦男

  Fukushima Research Laboratories Toa Eiyo Ltd.

• 柴崎 正勝

  Faculty Of Pharmaceutical Sciences Hokkaido University:(present Address)faculty Of Phamaceutical Sci

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