Application of Remote Photocyclization with a Pair System of Phthalimide and Methylthio Groups. A Photochemical Synthesis of Cyclic Peptide Models

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概要

• 論文の詳細を見る

• Application of regioselective remote photocyclization of a pair system consisting of a phthalimide group and a methylthio group to a homologous series of N-substituted phthalimides (4 and 5) possessing a terminal sulfide function in the amide side chain was investigated. On irradiation, medium to large membered cyclic peptide-like compunds (6,7 and 9), up to a thirty-eight membered ring product (6f), were synthesized in moderate yields.

• 社団法人日本薬学会の論文
• 1992-12-25

著者

• 仲井 英雄

  Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.

• 和田 征夫

  Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.

• 和田 征夫

  Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.

• 佐藤 泰彦

  Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.,

• 溝口 富茂

  Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.,

• 畑中 保丸

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 金岡 祐一

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 佐藤 泰彦

  Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.

• 仲井 英雄

  Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.

• 仲井 英夫

  田辺製薬研

• 中井 英雄

  Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.

• 溝口 富茂

  Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.

• Nakai H

  Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.

• 金岡 祐一

  Toyama Women's College

• 畑中 保丸

  富山医科薬学大学和漢薬研究所

• 畑中 保丸

  Faculty Of Pharmaceutical Sciences Hokkaido University

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