The Norrish Type II Reaction of Thiophthalimides Having a Benzylic Hydrogen in an N-Alkyl Side Chain

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概要

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• Upon irradiation, thiophthalimides (4 and 5) possessing an N-ω-phenylalkyl substituent undergo the Norrish type II cyclization to give tricyclic isoindole derivatives (6-8).In the case of thiophthalimides (11) possessing an indene in the N-side chain, two competitive pathways, the Norrish type II and a Paterno-Buchi like type, were observed.

• 公益社団法人日本薬学会の論文
• 1989-03-25

著者

• 金岡 祐一

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 吉田 栄一

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 町田 實

  北海道医療大学歯学部

• 金岡 祐一

  Toyama Women's College

• 金岡 裕一

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 町田 實

  Faculty of Pharmaceutical Sciences, Higashi Nippon Gakuen University

• 町田 實

  Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University

• 小田 和明

  Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University

• 大野 孝正

  Faculty of Pharmaceutical Sciences Kyoto University

• 大野 孝正

  Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University

• 小田 和明

  北海道医療大学歯学部

• 小田 和明

  北海道医療大学薬学部薬化学教室

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