Heterocycles related to Nucleotides. VI. Photochemistry of Thiopyrimidines : Photoreduction of Thiouracils and Thiouridines with Sodium Borohydride
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概要
- 論文の詳細を見る
On ultraviolet irradiation in the presence of sodium borohydride, 4-thiouracil (1a), 4-thiouridine (1b) and 2-thiouracil (3a) were readily reduced to 2-oxohexahydropyrimidine (2a), its riboside (2b) and 1-(3-hydroxypropyl) thiourea (4), respectively. By controling the energies of the ultraviolet light in the region below 300 nm the selective photoreduction of these thiopyrimidines was demonstrated, while uracil and uridine were unaffected under these conditions. Photochemical behavior of the thiopyrimidines was discussed.
- 公益社団法人日本薬学会の論文
- 1974-04-25
著者
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金岡 祐一
Faculty of Pharmaceutical Sciences, Hokkaido University
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佐藤 英助
Faculty Of Pharmaceutical Sciences Hokkaido University:(present Address)department Of Technology Aom
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