A New Conversion Method from (-)-Limonene to Nepetalactones
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概要
- 論文の詳細を見る
This paper describes the conversions of (-)-limonene to four nepetalactones (1,2,ent-3 and 4) in a stereocontrolled manner. The cis-3,4-disubstituted cyclopentanone (5) obtained from (-)-limonene via Rh(I)-catalyzed cyclization of the 4-pentenal, could be converted to the bicyclo[3.3.0]octenone (6). After the stereoselective conversion of 6 into the diastereomeric isomers of the ketones (8 and 16), a sequence of reactions involving the silyl enol ethers (18 and 19), ozonolysis, and subsequent lactonization afforded the target molecules.
- 公益社団法人日本薬学会の論文
- 1988-01-25
著者
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末宗 洋
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty Of Pharmaceutical Sciences Kyushu University
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佐伯 清太郎
Faculty of Pharmaceutical Sciences, Kyushu University
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末宗 洋
九州大学薬学部
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末宗 洋
九州大学大学院薬学府
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佐伯 清太郎
Faculty Of Pharmaceutical Sciences Kyushu University
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小田 晃造
Faculty of Pharmaceutical Sciences, Kyushu University
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末宗 洋
九州大学大学院薬学研究院
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小田 晃造
Faculty Of Pharmaceutical Sciences Kyushu University
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