Diastereoselective Synthesis of Chiral 2,2,4-Trisubstituted 1,3-Dioxanes
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概要
- 論文の詳細を見る
Diastereoselective acetalization of methyl pyruvate and methyl phenylformate with (R)-1,3-butanediol afforded predominantly (2R, 4R)-2-methoxycarbonyl-2,4-dimethyl (or 4-methyl-2-phenyl)-1,3-dioxanes (1a, 4a) under thermodynamically controlled conditions. The (2S, 4R)-isomer (1b) was obtained as the major product under kinetically controlled conditions.
- 社団法人日本薬学会の論文
- 1990-11-25
著者
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末宗 洋
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty Of Pharmaceutical Sciences Kyushu University
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田中 直樹
Faculty of Pharmaceutical Sciences, Kyushu University
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田中 直樹
Faculty Of Science Shimane University
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末宗 洋
九州大学薬学部
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末宗 洋
九州大学大学院薬学府
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末宗 洋
九州大学大学院薬学研究院
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