A Stereocontrolled Synthesis of Trisubstituted Cyclohexanes and Cyclopentanes. Its Application to the Synthesis of 11-Deoxyprostaglandins
スポンサーリンク
概要
- 論文の詳細を見る
1,4-Addition of organocopper reagents to γ-substituted α, β-unsaturated γ-lactones followed by intramolecular trapping of the resulted enolates afforded cis, cis-1,2,3-trisubstituted cyclopentanes and cyclohexanes in a stereocontrolled manner. This new cyclization reaction to cyclopentanes provides a new synthetic route to the key intermediate in the synthesis of 11-deoxyprostaglandins.
- 社団法人日本薬学会の論文
- 1989-05-25
著者
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末宗 洋
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty Of Pharmaceutical Sciences Kyushu University
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肥塚 美千代
Faculty of Pharmaceutical Sciences, Kyushu University
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方 成林
Faculty of Pharmaceutical Sciences, Kyushu University
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末宗 洋
九州大学薬学部
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方 成林
Faculty Of Pharmaceutical Sciences Kyushu University
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末宗 洋
九州大学大学院薬学府
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肥塚 美千代
Faculty Of Pharmaceutical Sciences Kyushu University
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末宗 洋
九州大学大学院薬学研究院
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