Synthetic Approach to 1,3-Polymethyl Function Based on Diastereoselective Conjugate Addition
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概要
- 論文の詳細を見る
A new method for diastereo- and enantioselective preparation of 1,3-polymethyl functions was studied. The reaction of (1'R, 2'R, 5R)-(2E)-2'-hydroxycyclohexyl 5,9-dimethyl-2,8-decadienoate (6) with Me_2 CuLi afforded a diastereomeric mixture of conjugate addition products ((3R, 5R)-9 and (3S, 5R)-9) in a ratio of 77 to 23.
- 社団法人日本薬学会の論文
- 1993-09-15
著者
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末宗 洋
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty Of Pharmaceutical Sciences Kyushu University
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小川 知行
Faculty Of Pharmaceutical Sciences Kyushu University
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末宗 洋
九州大学薬学部
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末宗 洋
九州大学大学院薬学府
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末宗 洋
九州大学大学院薬学研究院
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