Conversion of Limonene to Prostanoic Acid and 8-Isoprostanoic Acid
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概要
- 論文の詳細を見る
Prostanoic acid (18) and 8-isoprostanoic acid (1) constitute the basic structures of primary prostaglandins and 8-isoprostaglandins. The conversion of commercially available (+)- and (-)-limonene to these compounds was accomplilshed by a sequence of reactions involving the Rh(I)-catalyzed cyclization of 3,4-disubstituted 4-pentenals, which were easily prepared from (+)- or (-)-limonene, to cis-3,4-disubstituted cyclopentanones and the appropriate modification of substituents on the five-membered ring.
- 公益社団法人日本薬学会の論文
- 1986-02-25
著者
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末宗 洋
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty Of Pharmaceutical Sciences Kyushu University
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末宗 洋
九州大学薬学部
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川原 哲也
Faculty Of Pharmaceutical Sciences Kyushu University
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末宗 洋
九州大学大学院薬学研究院
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