Preparation of Chiral, Highly Functionalized Cyclopentanes and Its Application to the Synthesis of Prostaglandin E_1
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概要
- 論文の詳細を見る
This paper describes the preparation of the polyfunctionalized cyclopentane ((±)-5) by silica gel-catalyzed air-oxidation, and its kinetic resolution by means of microbial reduction with Rhodotorula rubta to afford optically pure (-)-5 (>99% ee). Starting with (-)-5,a new route to prostaglandin E_1 was established.
- 社団法人日本薬学会の論文
- 1989-08-25
著者
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末宗 洋
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty of Pharmaceutical Sciences, Kyushu University
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酒井 浄
Faculty Of Pharmaceutical Sciences Kyushu University
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岡野 耕二
Faculty of Pharmaceutical Sciences, Kyushu University
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末宗 洋
九州大学薬学部
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岡野 耕二
Life Science Research Laboratory Japan Tobacco Inc.
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末宗 洋
九州大学大学院薬学府
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末宗 洋
九州大学大学院薬学研究院
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