Studies on 1,3-Dithiolium Cations. I. A Novel Synthetic Method of 4-p-Substituted Phenyl Derivatives and Related Compounds
スポンサーリンク
概要
- 論文の詳細を見る
A convenient method for the preparation of 4-p-substituted phenyl-1,3-dithiolium salts was presented. 4-p-Substituted phenacyl N, N-dialkylaminocarbodithioates easily obtained from the reaction of N, N-dialkylamine N, N-dialkylaminocarbodithioates and p-substituted phenacylbromides were cyclized to give 2-immonium 1,3-dithiole salts. Reduction of immonium salts was performed by the action of NaBH_4 to give 2-amino-1,3-dithiole and the action of acid to this amine gave 1,3-dithiolium salts immediately. The yield of each step was very high and the operation was simple, giving pure 1,3-dithiolium salts. The properties of intermediates and 4-p-substituted phenyl-1,3-dithiolium salts were described.
- 公益社団法人日本薬学会の論文
- 1969-09-25
著者
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平井 健太郎
Shionogi Research Laboratory, Shionogi & Co., Ltd.
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高見沢 映
Shionogi Research Laboratory Shionogi And Co. Ltd.
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高見沢 映
Shionogi Research Laboratory Shionogi & Co. Ltd.
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