Reactions of 2-Dialkylamino-5-phenyl-1,3-oxathiolium Cation with Nucleophiles Containing an Amino Group
スポンサーリンク
概要
- 論文の詳細を見る
Reactions of 2-dialkylamino-1,3-oxathiolium (I) with amino-nucleophiles provide simple access to a variety of heterocyclic compounds. Thiadiazines and thiazoles were readily obtained from the reaction with hydrazines and ammonia, respectively. The intermediates, which were easily converted into thiazoles, were also isolated. Study of the reaction of 1 with aromatic amines revealed the formation of ring-opened ketones and 2-arylimino-1,3-oxathioles depending upon the reaction conditions. Reactions of I with aromatic and aliphatic amines in boiling glacial acetic acid resulted in the formation of 2-iminothiazoline derivatives.
- 公益社団法人日本薬学会の論文
- 1978-10-25
著者
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平井 健太郎
塩野義製薬研究所
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平井 健太郎
Shionogi Research Laboratory, Shionogi & Co., Ltd.
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石破 暉之
Shionogi Research Laboratory, Shionogi & Co., Ltd.
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石破 暉之
塩野義製薬(株)研
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石破 暉之
Shionogi Research Laboratory Shionogi & Co. Ltd.
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