Syntheses of Pyrazole Derivatives. IX. Acetylation Products of 7-Aminopyrazolo [1,5-α] pyrimidines

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概要

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• The behaviours of 7-amino-2,3-dimethyl- and 7-amino-2,3,6-trimethylpyrazolo [1,5-α]-pyrimidines (I, II) against acylation and alkylation were investigated. Mono- and diacylates were obtained from II but only monoacylate from I, of which reason was considered due to the steric effect of the methyl group at the 6-position. The substitution position of acyl groups was confirmed to be at 7-amino group but alkyl groups at N-4 position, respectively, from their chemical and physical evidences. Their nuclear magnetic resonance and ultraviolet spectra were also discussed briefly.

• 公益社団法人日本薬学会の論文
• 1965-02-25

著者

• 浜島 好男

  Shionogi Research Laboratory Shionogi & Co. Ltd.

• 高見沢 映

  Shionogi Research Laboratory Shionogi & Co. Ltd.

関連論文

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